A preliminary study on the early axial length of premature infants without retinopathy of premature infants

AIM: To investigate the axial length(AL)of normal premature infants, and to analyze the associations with gender, gestational age, birth weight, and postmenstrual age and other ocular biometry parameters. <p>METHODS: To analyze AL and other relevant data obtained from the first examination wit...

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Main Authors: Qian Wang, Cong-Hui Li, Ai-Jie Pan, Wei Xin, Jing Yang, Wen-Qing Shang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-10-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2018/10/201810040.pdf
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author Qian Wang
Cong-Hui Li
Ai-Jie Pan
Wei Xin
Jing Yang
Wen-Qing Shang
author_facet Qian Wang
Cong-Hui Li
Ai-Jie Pan
Wei Xin
Jing Yang
Wen-Qing Shang
author_sort Qian Wang
collection DOAJ
description AIM: To investigate the axial length(AL)of normal premature infants, and to analyze the associations with gender, gestational age, birth weight, and postmenstrual age and other ocular biometry parameters. <p>METHODS: To analyze AL and other relevant data obtained from the first examination within 4-6wk after birth, 400 cases(800 eyes)of normal preterm infants were included who were screened for retinopathy of prematurity(ROP)in Department of Ophthalmology of Northwest Women and Children Hospital from March 2016 to October 2016. <p>RESULTS: Totally 400 cases(800 eyes)of normal preterm infants were included in this study, while the AL of right and left eyes were respectively 16.11±0.58mm and 16.13±0.53mm, with no statistically significant difference(<i>P</i>>0.05). Therefore, the mean value(16.12±0.55mm)of the binocular AL was taken as the AL of the group. In this study, AL differences of premature infants between different genders were not statistically significant(<i>P</i>>0.05). Pearson correlation analysis showed that AL was positively correlated with the gestational age, birth weight, postmenstrual age, anterior chamber depth and vitreous length(<i>r</i>=0.427, 0.401, 0.635, 0.691, 0.878; <i>P</i><0.01), and negatively correlated with lens thickness(<i>r</i>=-0.153, <i>P</i><0.01). By incorporating the above factors into the multiple linear regression analysis, it was found that AL was significantly correlated with gestational age, anterior chamber depth, and vitreous length, and the regression equation <i>Y</i>=4.109+0.029<i>X<sub>1</sub></i>+0.481<i>X<sub>2</sub></i>+0.978<i>X<sub>3</sub></i>(<i>Y</i>=AL, <i>X<sub>1</sub></i>=gestational age, <i>X<sub>2</sub></i>=anterior chamber depth, <i>X<sub>3</sub></i>=vitreous length)was obtained.<p>CONCLUSION: In the early stage of normal premature infants, the mean AL was 16.12±0.55mm, which was not related to gender, but positively correlated with gestational age, birth weight, postmenstrual age, anterior chamber depth, and vitreous length, and negatively correlated with lens thickness.
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spelling doaj.art-450ffe25a16448abb1e589e1c39ab7442022-12-21T18:35:51ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232018-10-0118101915191710.3980/j.issn.1672-5123.2018.10.40A preliminary study on the early axial length of premature infants without retinopathy of premature infantsQian Wang0Cong-Hui Li1Ai-Jie Pan2Wei Xin3Jing Yang4Wen-Qing Shang5Department of Ophthalmology, Northwest Women and Children Hospital, Xi'an 710061, Shaanxi Province, ChinaDepartment of Ophthalmology, Northwest Women and Children Hospital, Xi'an 710061, Shaanxi Province, ChinaDepartment of Ophthalmology, Northwest Women and Children Hospital, Xi'an 710061, Shaanxi Province, ChinaDepartment of Ophthalmology, Northwest Women and Children Hospital, Xi'an 710061, Shaanxi Province, ChinaDepartment of Ophthalmology, Northwest Women and Children Hospital, Xi'an 710061, Shaanxi Province, ChinaDepartment of Ophthalmology, Northwest Women and Children Hospital, Xi'an 710061, Shaanxi Province, ChinaAIM: To investigate the axial length(AL)of normal premature infants, and to analyze the associations with gender, gestational age, birth weight, and postmenstrual age and other ocular biometry parameters. <p>METHODS: To analyze AL and other relevant data obtained from the first examination within 4-6wk after birth, 400 cases(800 eyes)of normal preterm infants were included who were screened for retinopathy of prematurity(ROP)in Department of Ophthalmology of Northwest Women and Children Hospital from March 2016 to October 2016. <p>RESULTS: Totally 400 cases(800 eyes)of normal preterm infants were included in this study, while the AL of right and left eyes were respectively 16.11±0.58mm and 16.13±0.53mm, with no statistically significant difference(<i>P</i>>0.05). Therefore, the mean value(16.12±0.55mm)of the binocular AL was taken as the AL of the group. In this study, AL differences of premature infants between different genders were not statistically significant(<i>P</i>>0.05). Pearson correlation analysis showed that AL was positively correlated with the gestational age, birth weight, postmenstrual age, anterior chamber depth and vitreous length(<i>r</i>=0.427, 0.401, 0.635, 0.691, 0.878; <i>P</i><0.01), and negatively correlated with lens thickness(<i>r</i>=-0.153, <i>P</i><0.01). By incorporating the above factors into the multiple linear regression analysis, it was found that AL was significantly correlated with gestational age, anterior chamber depth, and vitreous length, and the regression equation <i>Y</i>=4.109+0.029<i>X<sub>1</sub></i>+0.481<i>X<sub>2</sub></i>+0.978<i>X<sub>3</sub></i>(<i>Y</i>=AL, <i>X<sub>1</sub></i>=gestational age, <i>X<sub>2</sub></i>=anterior chamber depth, <i>X<sub>3</sub></i>=vitreous length)was obtained.<p>CONCLUSION: In the early stage of normal premature infants, the mean AL was 16.12±0.55mm, which was not related to gender, but positively correlated with gestational age, birth weight, postmenstrual age, anterior chamber depth, and vitreous length, and negatively correlated with lens thickness.http://ies.ijo.cn/cn_publish/2018/10/201810040.pdfpremature infantsaxial lengthgestational agebirth weightpostmenstrual ageanterior chamber depthlens thicknessvitreous lengthvitreous length
spellingShingle Qian Wang
Cong-Hui Li
Ai-Jie Pan
Wei Xin
Jing Yang
Wen-Qing Shang
A preliminary study on the early axial length of premature infants without retinopathy of premature infants
Guoji Yanke Zazhi
premature infants
axial length
gestational age
birth weight
postmenstrual age
anterior chamber depth
lens thickness
vitreous length
vitreous length
title A preliminary study on the early axial length of premature infants without retinopathy of premature infants
title_full A preliminary study on the early axial length of premature infants without retinopathy of premature infants
title_fullStr A preliminary study on the early axial length of premature infants without retinopathy of premature infants
title_full_unstemmed A preliminary study on the early axial length of premature infants without retinopathy of premature infants
title_short A preliminary study on the early axial length of premature infants without retinopathy of premature infants
title_sort preliminary study on the early axial length of premature infants without retinopathy of premature infants
topic premature infants
axial length
gestational age
birth weight
postmenstrual age
anterior chamber depth
lens thickness
vitreous length
vitreous length
url http://ies.ijo.cn/cn_publish/2018/10/201810040.pdf
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