STING agonist cGAMP enhances anti-tumor activity of CAR-NK cells against pancreatic cancer

STING agonist cGAMP enhances anti-tumor activity of CAR-NK cells against pancreatic cancer

Activation of the stimulator of interferon gene (STING)-mediated innate immune response has been suggested as a promising therapeutic strategy for cancers. However, the effects of STING agonist on natural killer (NK) cell-mediated anti-tumor responses in pancreatic cancer remains unknown. Herein, we...

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Bibliographic Details
Main Authors: Yanyan Da, Yuxia Liu, Yuan Hu, Wenzeng Liu, Junpeng Ma, Nan Lu, Chengsheng Zhang, Cai Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:OncoImmunology
Subjects:
STING
STING agonist
cGAMP
pancreatic cancer
CAR-NK-92 cells
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2054105

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