Polymeric nanoparticles—Promising carriers for cancer therapy
Polymeric nanoparticles (NPs) play an important role in controlled cancer drug delivery. Anticancer drugs can be conjugated or encapsulated by polymeric nanocarriers, which are known as polymeric nanomedicine. Polymeric nanomedicine has shown its potential in providing sustained release of drugs wit...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2022-10-01
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Series: | Frontiers in Bioengineering and Biotechnology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.1024143/full |
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author | Xiao Xiao Fei Teng Changkuo Shi Junyu Chen Shuqing Wu Bao Wang Xiang Meng Aniekan Essiet Imeh Wenliang Li Wenliang Li |
author_facet | Xiao Xiao Fei Teng Changkuo Shi Junyu Chen Shuqing Wu Bao Wang Xiang Meng Aniekan Essiet Imeh Wenliang Li Wenliang Li |
author_sort | Xiao Xiao |
collection | DOAJ |
description | Polymeric nanoparticles (NPs) play an important role in controlled cancer drug delivery. Anticancer drugs can be conjugated or encapsulated by polymeric nanocarriers, which are known as polymeric nanomedicine. Polymeric nanomedicine has shown its potential in providing sustained release of drugs with reduced cytotoxicity and modified tumor retention, but until now, few delivery systems loading drugs have been able to meet clinical demands, so more efforts are needed. This research reviews the current state of the cancer drug-loading system by exhibiting a series of published articles that highlight the novelty and functions from a variety of different architectures including micelles, liposomes, dendrimers, polymersomes, hydrogels, and metal–organic frameworks. These may contribute to the development of useful polymeric NPs to achieve different therapeutic purposes. |
first_indexed | 2024-04-13T19:54:23Z |
format | Article |
id | doaj.art-45166268316f4b0bae50e0708df0997a |
institution | Directory Open Access Journal |
issn | 2296-4185 |
language | English |
last_indexed | 2024-04-13T19:54:23Z |
publishDate | 2022-10-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Bioengineering and Biotechnology |
spelling | doaj.art-45166268316f4b0bae50e0708df0997a2022-12-22T02:32:23ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-10-011010.3389/fbioe.2022.10241431024143Polymeric nanoparticles—Promising carriers for cancer therapyXiao Xiao0Fei Teng1Changkuo Shi2Junyu Chen3Shuqing Wu4Bao Wang5Xiang Meng6Aniekan Essiet Imeh7Wenliang Li8Wenliang Li9School of Pharmacy, Jilin Medical University, Jilin, ChinaSchool of Pharmacy, Jilin Medical University, Jilin, ChinaSchool of Pharmacy, Jilin Medical University, Jilin, ChinaSchool of Pharmacy, Jilin Medical University, Jilin, ChinaSchool of Pharmacy, Jilin Medical University, Jilin, ChinaSchool of Chemistry and Environmental Engineering, Changchun University of Science and Technology, Changchun, ChinaSchool of Pharmacy, Jilin Medical University, Jilin, ChinaSchool of Clinical Medicine, Jilin Medical University, Jilin, ChinaSchool of Pharmacy, Jilin Medical University, Jilin, ChinaJilin Collaborative Innovation Center for Antibody Engineering, Jilin Medical University, Jilin, ChinaPolymeric nanoparticles (NPs) play an important role in controlled cancer drug delivery. Anticancer drugs can be conjugated or encapsulated by polymeric nanocarriers, which are known as polymeric nanomedicine. Polymeric nanomedicine has shown its potential in providing sustained release of drugs with reduced cytotoxicity and modified tumor retention, but until now, few delivery systems loading drugs have been able to meet clinical demands, so more efforts are needed. This research reviews the current state of the cancer drug-loading system by exhibiting a series of published articles that highlight the novelty and functions from a variety of different architectures including micelles, liposomes, dendrimers, polymersomes, hydrogels, and metal–organic frameworks. These may contribute to the development of useful polymeric NPs to achieve different therapeutic purposes.https://www.frontiersin.org/articles/10.3389/fbioe.2022.1024143/fullpolymeric nanoparticlenanocarriercancer drug deliverythermo-sensitivepH-sensitive |
spellingShingle | Xiao Xiao Fei Teng Changkuo Shi Junyu Chen Shuqing Wu Bao Wang Xiang Meng Aniekan Essiet Imeh Wenliang Li Wenliang Li Polymeric nanoparticles—Promising carriers for cancer therapy Frontiers in Bioengineering and Biotechnology polymeric nanoparticle nanocarrier cancer drug delivery thermo-sensitive pH-sensitive |
title | Polymeric nanoparticles—Promising carriers for cancer therapy |
title_full | Polymeric nanoparticles—Promising carriers for cancer therapy |
title_fullStr | Polymeric nanoparticles—Promising carriers for cancer therapy |
title_full_unstemmed | Polymeric nanoparticles—Promising carriers for cancer therapy |
title_short | Polymeric nanoparticles—Promising carriers for cancer therapy |
title_sort | polymeric nanoparticles promising carriers for cancer therapy |
topic | polymeric nanoparticle nanocarrier cancer drug delivery thermo-sensitive pH-sensitive |
url | https://www.frontiersin.org/articles/10.3389/fbioe.2022.1024143/full |
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