MiR-181b suppress glioblastoma multiforme growth through inhibition of SP1-mediated glucose metabolism

MiR-181b suppress glioblastoma multiforme growth through inhibition of SP1-mediated glucose metabolism

Abstract Background Glucose metabolic reprogramming is a significant hallmark of malignant tumors including GBM. Previous studies suggest that microRNAs play key roles in modulating this process in GBM cells. miR-181b acts as a tumor suppressor miRNA in influencing glioma tumorigenesis. Our previous...

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Bibliographic Details
Main Authors: JianXing Yin, ZhuMei Shi, WenJin Wei, Chenfei Lu, Yutian Wei, Wei Yan, Rui Li, JunXia Zhang, YongPing You, XieFeng Wang
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cancer Cell International
Subjects:
miR-181b
SP1
Glucose metabolism
Glioma
Online Access:http://link.springer.com/article/10.1186/s12935-020-1149-7

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