Prevalence of hemoglobinopathies in pregnant women, Sancti Spíritus province
Introduction: hemoglobinopathies are a group of genetic diseases, caused by disorders in the structure of hemoglobin chains. The Cuban National Health System's priority is the early diagnosis of these diseases. Objectives: to characterize the behavior of hemoglobinopathies in pregnant women in...
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| Format: | Article |
| Language: | English |
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Universidad de Ciencias Médicas de Pinar del Río
2020-07-01
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| Series: | Universidad Médica Pinareña |
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| Online Access: | http://www.revgaleno.sld.cu/index.php/ump/article/view/558 |
| _version_ | 1797720409566609408 |
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| author | Abel Ernesto Luna-López Beatriz Concepción-Yero Lucía Beatriz Yero-Muro Ángela Elena Zúñiga-García Maday Martín-Pérez |
| author_facet | Abel Ernesto Luna-López Beatriz Concepción-Yero Lucía Beatriz Yero-Muro Ángela Elena Zúñiga-García Maday Martín-Pérez |
| author_sort | Abel Ernesto Luna-López |
| collection | DOAJ |
| description | Introduction: hemoglobinopathies are a group of genetic diseases, caused by disorders in the structure of hemoglobin chains. The Cuban National Health System's priority is the early diagnosis of these diseases.
Objectives: to characterize the behavior of hemoglobinopathies in pregnant women in Sancti Spíritus province in the period from 2011 to 2018.
Methods: an observational, descriptive, longitudinal and retrospective study was conducted using the databases of the Provincial Center of Medical Genetics of Sancti Spíritus. The universe consisted of 28 461 pregnant women who were studied and the sample was 756 pregnant women who presented some kind of hemoglobinopathies.
Results: out of the total number of pregnant women studied, 2,56 % were carriers of hemoglobinopathies, 90,60 % of the couples were studied and a total of 32 couples on risk were diagnosed and genetically counseled. The most common variants of hemoglobinopathies were AS (79,89 %) and AC (14,42 %). The municipalities with the highest number of hemoglobinopathies carriers were Sancti Spíritus (30,03 %) and Trinidad (28,70 %).
Conclusions: the prevalence of hemoglobinopathies in pregnant women in Sancti Spíritus province was described. A low prevalence of hemoglobinopathies is shown in pregnant women from Sancti Spíritus province. |
| first_indexed | 2024-03-12T09:20:02Z |
| format | Article |
| id | doaj.art-451adac03c6041d1816e39b49d0fd43f |
| institution | Directory Open Access Journal |
| issn | 1990-7990 |
| language | English |
| last_indexed | 2024-03-12T09:20:02Z |
| publishDate | 2020-07-01 |
| publisher | Universidad de Ciencias Médicas de Pinar del Río |
| record_format | Article |
| series | Universidad Médica Pinareña |
| spelling | doaj.art-451adac03c6041d1816e39b49d0fd43f2023-09-02T14:36:16ZengUniversidad de Ciencias Médicas de Pinar del RíoUniversidad Médica Pinareña1990-79902020-07-01163e558e558495Prevalence of hemoglobinopathies in pregnant women, Sancti Spíritus provinceAbel Ernesto Luna-López0Beatriz Concepción-Yero1Lucía Beatriz Yero-Muro2Ángela Elena Zúñiga-García3Maday Martín-Pérez4Universidad de Ciencias Médicas de Sancti Spíritus. Facultad de Ciencias Médicas "Dr. Faustino Pérez Hernández". Sancti SpíritusUniversidad de Ciencias Médicas de Sancti Spíritus. Hospital Universitario Clínico Quirúrgico Provincial “Camilo Cienfuegos”. Sancti SpíritusCentro Provincial de Genética Médica de Sancti Spíritus. Sancti SpíritusUniversidad de Ciencias Médicas de Sancti Spíritus. Hospital Universitario Clínico Quirúrgico Provincial “Camilo Cienfuegos”. Sancti SpíritusUniversidad de Ciencias Médicas de Sancti Spíritus. Hospital Universitario Clínico Quirúrgico Provincial “Camilo Cienfuegos”. Sancti SpíritusIntroduction: hemoglobinopathies are a group of genetic diseases, caused by disorders in the structure of hemoglobin chains. The Cuban National Health System's priority is the early diagnosis of these diseases. Objectives: to characterize the behavior of hemoglobinopathies in pregnant women in Sancti Spíritus province in the period from 2011 to 2018. Methods: an observational, descriptive, longitudinal and retrospective study was conducted using the databases of the Provincial Center of Medical Genetics of Sancti Spíritus. The universe consisted of 28 461 pregnant women who were studied and the sample was 756 pregnant women who presented some kind of hemoglobinopathies. Results: out of the total number of pregnant women studied, 2,56 % were carriers of hemoglobinopathies, 90,60 % of the couples were studied and a total of 32 couples on risk were diagnosed and genetically counseled. The most common variants of hemoglobinopathies were AS (79,89 %) and AC (14,42 %). The municipalities with the highest number of hemoglobinopathies carriers were Sancti Spíritus (30,03 %) and Trinidad (28,70 %). Conclusions: the prevalence of hemoglobinopathies in pregnant women in Sancti Spíritus province was described. A low prevalence of hemoglobinopathies is shown in pregnant women from Sancti Spíritus province.http://www.revgaleno.sld.cu/index.php/ump/article/view/558hemoglobinopatíaselectroforesis de las proteínas sanguíneasanemia de células falciformes. |
| spellingShingle | Abel Ernesto Luna-López Beatriz Concepción-Yero Lucía Beatriz Yero-Muro Ángela Elena Zúñiga-García Maday Martín-Pérez Prevalence of hemoglobinopathies in pregnant women, Sancti Spíritus province Universidad Médica Pinareña hemoglobinopatías electroforesis de las proteínas sanguíneas anemia de células falciformes. |
| title | Prevalence of hemoglobinopathies in pregnant women, Sancti Spíritus province |
| title_full | Prevalence of hemoglobinopathies in pregnant women, Sancti Spíritus province |
| title_fullStr | Prevalence of hemoglobinopathies in pregnant women, Sancti Spíritus province |
| title_full_unstemmed | Prevalence of hemoglobinopathies in pregnant women, Sancti Spíritus province |
| title_short | Prevalence of hemoglobinopathies in pregnant women, Sancti Spíritus province |
| title_sort | prevalence of hemoglobinopathies in pregnant women sancti spiritus province |
| topic | hemoglobinopatías electroforesis de las proteínas sanguíneas anemia de células falciformes. |
| url | http://www.revgaleno.sld.cu/index.php/ump/article/view/558 |
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