Marburg virus is nature's wake-up call: A bird's-eye view
Marburg virus (MARV), a member of Filoviridae family, is notorious for causing Marburg virus disease (MVD), one of the deadliest known infectious diseases. Over the past five decades, more than 15 MVD outbreaks have been reported in the African countries, and this has been reported from Equatorial G...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Medicine in Microecology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590097824000053 |
| _version_ | 1827228905230041088 |
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| author | Sanjit Boora Sulochana Kaushik Jaya Parkash Yadav Samander Kaushik Dharmender Kumar |
| author_facet | Sanjit Boora Sulochana Kaushik Jaya Parkash Yadav Samander Kaushik Dharmender Kumar |
| author_sort | Sanjit Boora |
| collection | DOAJ |
| description | Marburg virus (MARV), a member of Filoviridae family, is notorious for causing Marburg virus disease (MVD), one of the deadliest known infectious diseases. Over the past five decades, more than 15 MVD outbreaks have been reported in the African countries, and this has been reported from Equatorial Guinea on February 2023. Few bat species like Rousettus aegyptiacus and Hipposideros caffer, among other members of the Chiroptera order, may serve as a natural reservoir for the virus, which can transmit the disease to humans and other mammals. In humans, severe infections have been reported due to MVD and are characterized by clinical symptoms such as abdominal pain, nausea, vomiting, pharyngitis, and diarrhea, eventually progressing to hemorrhagic manifestations. The disease carries an extremely high mortality and morbidity rate. Developing and implementing rapid, accurate, affordable, and efficient diagnostic and therapeutic measures is essential to address the substantial threat MARV poses. Increased focus on health education, enhancement of laboratory services and facilities, adherence to patient safety protocols, and robust surveillance systems are urgently needed to combat this fatal disease. This review aims to present a comprehensive summary of the various attributes and characteristics of MARV/MVD, along with strategies for its prevention and control. Further, this review article also discusses the potential role of medicinal plants in addressing health challenge. |
| first_indexed | 2024-03-07T13:59:55Z |
| format | Article |
| id | doaj.art-4521855e79834077bea133d932e6eef3 |
| institution | Directory Open Access Journal |
| issn | 2590-0978 |
| language | English |
| last_indexed | 2025-03-21T18:21:17Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medicine in Microecology |
| spelling | doaj.art-4521855e79834077bea133d932e6eef32024-06-09T05:29:09ZengElsevierMedicine in Microecology2590-09782024-06-0120100102Marburg virus is nature's wake-up call: A bird's-eye viewSanjit Boora0Sulochana Kaushik1Jaya Parkash Yadav2Samander Kaushik3Dharmender Kumar4Centre for Biotechnology, Maharshi Dayanand University, Rohtak, 124001, Haryana, IndiaDepartment of Genetics, Maharshi Dayanand University, Rohtak, 124001, Haryana, IndiaDepartment of Genetics, Maharshi Dayanand University, Rohtak, 124001, Haryana, IndiaCentre for Biotechnology, Maharshi Dayanand University, Rohtak, 124001, Haryana, India; Corresponding author.Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, 131039, Sonepat, Haryana, India; Corresponding author.Marburg virus (MARV), a member of Filoviridae family, is notorious for causing Marburg virus disease (MVD), one of the deadliest known infectious diseases. Over the past five decades, more than 15 MVD outbreaks have been reported in the African countries, and this has been reported from Equatorial Guinea on February 2023. Few bat species like Rousettus aegyptiacus and Hipposideros caffer, among other members of the Chiroptera order, may serve as a natural reservoir for the virus, which can transmit the disease to humans and other mammals. In humans, severe infections have been reported due to MVD and are characterized by clinical symptoms such as abdominal pain, nausea, vomiting, pharyngitis, and diarrhea, eventually progressing to hemorrhagic manifestations. The disease carries an extremely high mortality and morbidity rate. Developing and implementing rapid, accurate, affordable, and efficient diagnostic and therapeutic measures is essential to address the substantial threat MARV poses. Increased focus on health education, enhancement of laboratory services and facilities, adherence to patient safety protocols, and robust surveillance systems are urgently needed to combat this fatal disease. This review aims to present a comprehensive summary of the various attributes and characteristics of MARV/MVD, along with strategies for its prevention and control. Further, this review article also discusses the potential role of medicinal plants in addressing health challenge.http://www.sciencedirect.com/science/article/pii/S2590097824000053Marburg virus (MARV)EpidemiologyInfectious diseaseOutbreakMedicinal plant |
| spellingShingle | Sanjit Boora Sulochana Kaushik Jaya Parkash Yadav Samander Kaushik Dharmender Kumar Marburg virus is nature's wake-up call: A bird's-eye view Medicine in Microecology Marburg virus (MARV) Epidemiology Infectious disease Outbreak Medicinal plant |
| title | Marburg virus is nature's wake-up call: A bird's-eye view |
| title_full | Marburg virus is nature's wake-up call: A bird's-eye view |
| title_fullStr | Marburg virus is nature's wake-up call: A bird's-eye view |
| title_full_unstemmed | Marburg virus is nature's wake-up call: A bird's-eye view |
| title_short | Marburg virus is nature's wake-up call: A bird's-eye view |
| title_sort | marburg virus is nature s wake up call a bird s eye view |
| topic | Marburg virus (MARV) Epidemiology Infectious disease Outbreak Medicinal plant |
| url | http://www.sciencedirect.com/science/article/pii/S2590097824000053 |
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