The Combination of Galanin (1–15) and Escitalopram in Rats Suggests a New Strategy for Alcohol Use Disorder Comorbidity with Depression
Alcohol use disorder (AUD) is highly prevalent, and over 50% of AUD patients also suffer major depressive disorders. Selective 5-HT reuptake inhibitors (SSRIs) can reduce rodent ethanol drinking but exert modest clinical efficacy in alcoholic individuals. Finding new pharmacological strategies that...
Main Authors: | Noelia Cantero-García, Antonio Flores-Burgess, David Ladrón de Guevara-Miranda, Antonia Serrano, Laura García-Durán, Araceli Puigcerver, Kjell Fuxe, José Ángel Narváez, Luis Javier Santín, Zaida Díaz-Cabiale, Carmelo Millón |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-02-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/10/2/412 |
Similar Items
-
Galanin(1-15) Potentiates the Antidepressant-like Effects Induced by Escitalopram in a Rat Model of Depression
by: Laura García-Durán, et al.
Published: (2021-10-01) -
Galanin Receptors as Drug Target for Novel Antidepressants: Review
by: Demsie DG, et al.
Published: (2020-04-01) -
On the existence and function of galanin receptor heteromers in the Central Nervous System
by: Kjell eFuxe, et al.
Published: (2012-10-01) -
A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats
by: Manuel Narváez, et al.
Published: (2018-05-01) -
Galanin 2 Receptor: A Novel Target for a Subset of Pancreatic Ductal Adenocarcinoma
by: Pawel Namsolleck, et al.
Published: (2023-06-01)