The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males
Strenuous exercise induces organ damage, inflammation and oxidative stress. To prevent exercise-induced organ damage, inflammation and oxidative stress, rehydrating may be an effective strategy. In the present study, we aimed to examine whether beverage intake after exhaustive exercise to recover fr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/10/6/866 |
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| author | Takaki Tominaga Tsukasa Ikemura Koichi Yada Kazue Kanda Kaoru Sugama Sihui Ma Wonjun Choi Mayu Araya Jiapeng Huang Nobuhiro Nakamura Katsuhiko Suzuki |
| author_facet | Takaki Tominaga Tsukasa Ikemura Koichi Yada Kazue Kanda Kaoru Sugama Sihui Ma Wonjun Choi Mayu Araya Jiapeng Huang Nobuhiro Nakamura Katsuhiko Suzuki |
| author_sort | Takaki Tominaga |
| collection | DOAJ |
| description | Strenuous exercise induces organ damage, inflammation and oxidative stress. To prevent exercise-induced organ damage, inflammation and oxidative stress, rehydrating may be an effective strategy. In the present study, we aimed to examine whether beverage intake after exhaustive exercise to recover from dehydration prevents such disorders. Thirteen male volunteers performed incremental cycling exercise until exhaustion. Immediately after exercise, the subjects drank an electrolyte containing water (rehydrate trial: REH) or did not drink any beverage (control trial: CON). Blood samples were collected before (Pre), immediately (Post), 1 h and 2 h after exercise. Urine samples were also collected before (Pre) and 2 h after exercise. We measured biomarkers of organ damage, inflammation and oxidative stress in blood and urine. Biomarkers of muscle, renal and intestinal damage and inflammation increased in the blood and urine after exercise. However, changes in biomarkers of organ damage and inflammation did not differ between trials (<i>p</i> > 0.05). The biomarker of oxidative stress, thiobarbituric acid reactive substances (TBARS), in plasma, showed different changes between trials (<i>p</i> = 0.027). One hour after exercise, plasma TBARS concentration in REH had a higher trend than that in CON (<i>p</i> = 0.052), but there were no significant differences between Pre and the other time points in each trial. These results suggest that beverage intake after exercise does not attenuate exercise-induced organ damage, inflammation or oxidative stress in healthy males. However, rehydration restores exercise-induced oxidative stress more quickly. |
| first_indexed | 2024-03-10T10:56:27Z |
| format | Article |
| id | doaj.art-45243d8c10bb4d718eaf57fa476db565 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T10:56:27Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-45243d8c10bb4d718eaf57fa476db5652023-11-21T21:49:28ZengMDPI AGAntioxidants2076-39212021-05-0110686610.3390/antiox10060866The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy MalesTakaki Tominaga0Tsukasa Ikemura1Koichi Yada2Kazue Kanda3Kaoru Sugama4Sihui Ma5Wonjun Choi6Mayu Araya7Jiapeng Huang8Nobuhiro Nakamura9Katsuhiko Suzuki10Graduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanFuture Innovation Institute, Waseda University, Shinjuku 162-0041, JapanFuture Innovation Institute, Waseda University, Shinjuku 162-0041, JapanResearch Fellow of Japan Society for the Promotion of Sciences, Tokyo 102-0083, JapanGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanStrenuous exercise induces organ damage, inflammation and oxidative stress. To prevent exercise-induced organ damage, inflammation and oxidative stress, rehydrating may be an effective strategy. In the present study, we aimed to examine whether beverage intake after exhaustive exercise to recover from dehydration prevents such disorders. Thirteen male volunteers performed incremental cycling exercise until exhaustion. Immediately after exercise, the subjects drank an electrolyte containing water (rehydrate trial: REH) or did not drink any beverage (control trial: CON). Blood samples were collected before (Pre), immediately (Post), 1 h and 2 h after exercise. Urine samples were also collected before (Pre) and 2 h after exercise. We measured biomarkers of organ damage, inflammation and oxidative stress in blood and urine. Biomarkers of muscle, renal and intestinal damage and inflammation increased in the blood and urine after exercise. However, changes in biomarkers of organ damage and inflammation did not differ between trials (<i>p</i> > 0.05). The biomarker of oxidative stress, thiobarbituric acid reactive substances (TBARS), in plasma, showed different changes between trials (<i>p</i> = 0.027). One hour after exercise, plasma TBARS concentration in REH had a higher trend than that in CON (<i>p</i> = 0.052), but there were no significant differences between Pre and the other time points in each trial. These results suggest that beverage intake after exercise does not attenuate exercise-induced organ damage, inflammation or oxidative stress in healthy males. However, rehydration restores exercise-induced oxidative stress more quickly.https://www.mdpi.com/2076-3921/10/6/866acute exerciseorgan damageinflammationoxidative stressbeverage intakeendotoxin |
| spellingShingle | Takaki Tominaga Tsukasa Ikemura Koichi Yada Kazue Kanda Kaoru Sugama Sihui Ma Wonjun Choi Mayu Araya Jiapeng Huang Nobuhiro Nakamura Katsuhiko Suzuki The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males Antioxidants acute exercise organ damage inflammation oxidative stress beverage intake endotoxin |
| title | The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males |
| title_full | The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males |
| title_fullStr | The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males |
| title_full_unstemmed | The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males |
| title_short | The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males |
| title_sort | effects of beverage intake after exhaustive exercise on organ damage inflammation and oxidative stress in healthy males |
| topic | acute exercise organ damage inflammation oxidative stress beverage intake endotoxin |
| url | https://www.mdpi.com/2076-3921/10/6/866 |
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