Serum and tissue monocyte differentiation in PSA value 4–10 ng/mL prostate cancer and benign prostatic hyperplasia
Increased serum prostate-specific antigen (PSA) level is closely associated with prostate cancer; however, there is still no reliable method for distinguishing prostate cancer from benign prostatic hyperplasia (BPH) when the PSA level is between 4 and 10 ng/mL. In this study, we detected the inflamm...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2018-11-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/2058739218812665 |
| _version_ | 1818056766046339072 |
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| author | Yuanyuan Guo Beibei Liu Jianmin Liu Sheng Wang Rui Wang Rui Chang Wenyan Sun Tantu Ma Qingwen Li |
| author_facet | Yuanyuan Guo Beibei Liu Jianmin Liu Sheng Wang Rui Wang Rui Chang Wenyan Sun Tantu Ma Qingwen Li |
| author_sort | Yuanyuan Guo |
| collection | DOAJ |
| description | Increased serum prostate-specific antigen (PSA) level is closely associated with prostate cancer; however, there is still no reliable method for distinguishing prostate cancer from benign prostatic hyperplasia (BPH) when the PSA level is between 4 and 10 ng/mL. In this study, we detected the inflammatory cell counts in serum and prostate tissues in prostate cancer and BPH patients. The results showed that the monocyte counts in both serum and prostate tissues were obviously less in patients with prostate cancer than that in those with BPH, which indicates that monocyte may be associated with development of prostate cancer and it is possible to increase positive finding for prostate cancer with 4–10 ng/mL PSA concentration by detecting and analyzing monocyte count in serum and tissue simultaneously. |
| first_indexed | 2024-12-10T12:34:03Z |
| format | Article |
| id | doaj.art-4527111153154823ab9677a5d0c6f580 |
| institution | Directory Open Access Journal |
| issn | 2058-7392 |
| language | English |
| last_indexed | 2024-12-10T12:34:03Z |
| publishDate | 2018-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | European Journal of Inflammation |
| spelling | doaj.art-4527111153154823ab9677a5d0c6f5802022-12-22T01:48:43ZengSAGE PublishingEuropean Journal of Inflammation2058-73922018-11-011610.1177/2058739218812665Serum and tissue monocyte differentiation in PSA value 4–10 ng/mL prostate cancer and benign prostatic hyperplasiaYuanyuan Guo0Beibei Liu1Jianmin Liu2Sheng Wang3Rui Wang4Rui Chang5Wenyan Sun6Tantu Ma7Qingwen Li8Department of Urology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaDepartment of Urology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaDepartment of Urology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaDepartment of Urology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaDepartment of Medical Oncology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaDepartment of Urology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaDepartment of Urology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaDepartment of Urology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaDepartment of Urology, First Affiliated Hospital of Bengbu Medical College, Bengbu, ChinaIncreased serum prostate-specific antigen (PSA) level is closely associated with prostate cancer; however, there is still no reliable method for distinguishing prostate cancer from benign prostatic hyperplasia (BPH) when the PSA level is between 4 and 10 ng/mL. In this study, we detected the inflammatory cell counts in serum and prostate tissues in prostate cancer and BPH patients. The results showed that the monocyte counts in both serum and prostate tissues were obviously less in patients with prostate cancer than that in those with BPH, which indicates that monocyte may be associated with development of prostate cancer and it is possible to increase positive finding for prostate cancer with 4–10 ng/mL PSA concentration by detecting and analyzing monocyte count in serum and tissue simultaneously.https://doi.org/10.1177/2058739218812665 |
| spellingShingle | Yuanyuan Guo Beibei Liu Jianmin Liu Sheng Wang Rui Wang Rui Chang Wenyan Sun Tantu Ma Qingwen Li Serum and tissue monocyte differentiation in PSA value 4–10 ng/mL prostate cancer and benign prostatic hyperplasia European Journal of Inflammation |
| title | Serum and tissue monocyte differentiation in PSA value 4–10 ng/mL prostate cancer and benign prostatic hyperplasia |
| title_full | Serum and tissue monocyte differentiation in PSA value 4–10 ng/mL prostate cancer and benign prostatic hyperplasia |
| title_fullStr | Serum and tissue monocyte differentiation in PSA value 4–10 ng/mL prostate cancer and benign prostatic hyperplasia |
| title_full_unstemmed | Serum and tissue monocyte differentiation in PSA value 4–10 ng/mL prostate cancer and benign prostatic hyperplasia |
| title_short | Serum and tissue monocyte differentiation in PSA value 4–10 ng/mL prostate cancer and benign prostatic hyperplasia |
| title_sort | serum and tissue monocyte differentiation in psa value 4 10 ng ml prostate cancer and benign prostatic hyperplasia |
| url | https://doi.org/10.1177/2058739218812665 |
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