Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators

Malignant tumor is are a kind of high-energy metabolic disease. Due to the role of malignant tumors themselves, the human body's stress response to malignant tumors and the measures in the anti-cancer treatment process lead to the special characteristics of cancer patients, such as lipolysis an...

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Main Authors: TANG Cuijuan, RONG Zhen, MO Chunmei, ZHENG Weiping
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2019-05-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1490.htm
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author TANG Cuijuan
RONG Zhen
MO Chunmei
ZHENG Weiping
author_facet TANG Cuijuan
RONG Zhen
MO Chunmei
ZHENG Weiping
author_sort TANG Cuijuan
collection DOAJ
description Malignant tumor is are a kind of high-energy metabolic disease. Due to the role of malignant tumors themselves, the human body's stress response to malignant tumors and the measures in the anti-cancer treatment process lead to the special characteristics of cancer patients, such as lipolysis and increased fatty acids oxidation, decreased lean tissue group, insulin resistance, and protein metabolism disorders etc. A large number of metabolites, such as lipopolysaccharide (LPS), lactic acid, arachidonic acid metabolite (PGE2), free fatty acid (FFA), etc., often induce chronic low-grade inflammation. Many tumors occur in the areas of infection, chronic irritation and inflammation, so the influence of the inflammatory microenvironment on tumors has become the focus in the field of scientific research. In the process of tumor body metabolism, many inflammatory mediators are involved, so this paper summarizes the relationship between tumor energy metabolism characteristics, tumor metabolic abnormalities and related inflammatory mediators.
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spelling doaj.art-452730718005422bbd8d5f0eceaf8ae02022-12-21T18:55:10ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85781000-85782019-05-0146547648110.3971/j.issn.1000-8578.2019.18.14908578.2019.18.1490Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory MediatorsTANG Cuijuan0RONG Zhen1MO Chunmei2ZHENG Weiping3Graduate School of Guangxi University of Traditional Chinese Medicine, Nanning 530000, ChinaDepartment of Oncology, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530000, ChinaDepartment of Hepatology, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530000, ChinaDepartment of Oncology, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530000, ChinaMalignant tumor is are a kind of high-energy metabolic disease. Due to the role of malignant tumors themselves, the human body's stress response to malignant tumors and the measures in the anti-cancer treatment process lead to the special characteristics of cancer patients, such as lipolysis and increased fatty acids oxidation, decreased lean tissue group, insulin resistance, and protein metabolism disorders etc. A large number of metabolites, such as lipopolysaccharide (LPS), lactic acid, arachidonic acid metabolite (PGE2), free fatty acid (FFA), etc., often induce chronic low-grade inflammation. Many tumors occur in the areas of infection, chronic irritation and inflammation, so the influence of the inflammatory microenvironment on tumors has become the focus in the field of scientific research. In the process of tumor body metabolism, many inflammatory mediators are involved, so this paper summarizes the relationship between tumor energy metabolism characteristics, tumor metabolic abnormalities and related inflammatory mediators.http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1490.htmmalignant tumormetabolisminflammatory mediatorsinflammatory microenvironment
spellingShingle TANG Cuijuan
RONG Zhen
MO Chunmei
ZHENG Weiping
Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators
Zhongliu Fangzhi Yanjiu
malignant tumor
metabolism
inflammatory mediators
inflammatory microenvironment
title Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators
title_full Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators
title_fullStr Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators
title_full_unstemmed Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators
title_short Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators
title_sort advances in metabolic characteristics of malignant tumors and their correlation with inflammatory mediators
topic malignant tumor
metabolism
inflammatory mediators
inflammatory microenvironment
url http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1490.htm
work_keys_str_mv AT tangcuijuan advancesinmetaboliccharacteristicsofmalignanttumorsandtheircorrelationwithinflammatorymediators
AT rongzhen advancesinmetaboliccharacteristicsofmalignanttumorsandtheircorrelationwithinflammatorymediators
AT mochunmei advancesinmetaboliccharacteristicsofmalignanttumorsandtheircorrelationwithinflammatorymediators
AT zhengweiping advancesinmetaboliccharacteristicsofmalignanttumorsandtheircorrelationwithinflammatorymediators