Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators
Malignant tumor is are a kind of high-energy metabolic disease. Due to the role of malignant tumors themselves, the human body's stress response to malignant tumors and the measures in the anti-cancer treatment process lead to the special characteristics of cancer patients, such as lipolysis an...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | zho |
Published: |
Magazine House of Cancer Research on Prevention and Treatment
2019-05-01
|
Series: | Zhongliu Fangzhi Yanjiu |
Subjects: | |
Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1490.htm |
_version_ | 1819073657514754048 |
---|---|
author | TANG Cuijuan RONG Zhen MO Chunmei ZHENG Weiping |
author_facet | TANG Cuijuan RONG Zhen MO Chunmei ZHENG Weiping |
author_sort | TANG Cuijuan |
collection | DOAJ |
description | Malignant tumor is are a kind of high-energy metabolic disease. Due to the role of malignant tumors themselves, the human body's stress response to malignant tumors and the measures in the anti-cancer treatment process lead to the special characteristics of cancer patients, such as lipolysis and increased fatty acids oxidation, decreased lean tissue group, insulin resistance, and protein metabolism disorders etc. A large number of metabolites, such as lipopolysaccharide (LPS), lactic acid, arachidonic acid metabolite (PGE2), free fatty acid (FFA), etc., often induce chronic low-grade inflammation. Many tumors occur in the areas of infection, chronic irritation and inflammation, so the influence of the inflammatory microenvironment on tumors has become the focus in the field of scientific research. In the process of tumor body metabolism, many inflammatory mediators are involved, so this paper summarizes the relationship between tumor energy metabolism characteristics, tumor metabolic abnormalities and related inflammatory mediators. |
first_indexed | 2024-12-21T17:57:06Z |
format | Article |
id | doaj.art-452730718005422bbd8d5f0eceaf8ae0 |
institution | Directory Open Access Journal |
issn | 1000-8578 1000-8578 |
language | zho |
last_indexed | 2024-12-21T17:57:06Z |
publishDate | 2019-05-01 |
publisher | Magazine House of Cancer Research on Prevention and Treatment |
record_format | Article |
series | Zhongliu Fangzhi Yanjiu |
spelling | doaj.art-452730718005422bbd8d5f0eceaf8ae02022-12-21T18:55:10ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85781000-85782019-05-0146547648110.3971/j.issn.1000-8578.2019.18.14908578.2019.18.1490Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory MediatorsTANG Cuijuan0RONG Zhen1MO Chunmei2ZHENG Weiping3Graduate School of Guangxi University of Traditional Chinese Medicine, Nanning 530000, ChinaDepartment of Oncology, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530000, ChinaDepartment of Hepatology, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530000, ChinaDepartment of Oncology, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530000, ChinaMalignant tumor is are a kind of high-energy metabolic disease. Due to the role of malignant tumors themselves, the human body's stress response to malignant tumors and the measures in the anti-cancer treatment process lead to the special characteristics of cancer patients, such as lipolysis and increased fatty acids oxidation, decreased lean tissue group, insulin resistance, and protein metabolism disorders etc. A large number of metabolites, such as lipopolysaccharide (LPS), lactic acid, arachidonic acid metabolite (PGE2), free fatty acid (FFA), etc., often induce chronic low-grade inflammation. Many tumors occur in the areas of infection, chronic irritation and inflammation, so the influence of the inflammatory microenvironment on tumors has become the focus in the field of scientific research. In the process of tumor body metabolism, many inflammatory mediators are involved, so this paper summarizes the relationship between tumor energy metabolism characteristics, tumor metabolic abnormalities and related inflammatory mediators.http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1490.htmmalignant tumormetabolisminflammatory mediatorsinflammatory microenvironment |
spellingShingle | TANG Cuijuan RONG Zhen MO Chunmei ZHENG Weiping Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators Zhongliu Fangzhi Yanjiu malignant tumor metabolism inflammatory mediators inflammatory microenvironment |
title | Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators |
title_full | Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators |
title_fullStr | Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators |
title_full_unstemmed | Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators |
title_short | Advances in Metabolic Characteristics of Malignant Tumors and Their Correlation with Inflammatory Mediators |
title_sort | advances in metabolic characteristics of malignant tumors and their correlation with inflammatory mediators |
topic | malignant tumor metabolism inflammatory mediators inflammatory microenvironment |
url | http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1490.htm |
work_keys_str_mv | AT tangcuijuan advancesinmetaboliccharacteristicsofmalignanttumorsandtheircorrelationwithinflammatorymediators AT rongzhen advancesinmetaboliccharacteristicsofmalignanttumorsandtheircorrelationwithinflammatorymediators AT mochunmei advancesinmetaboliccharacteristicsofmalignanttumorsandtheircorrelationwithinflammatorymediators AT zhengweiping advancesinmetaboliccharacteristicsofmalignanttumorsandtheircorrelationwithinflammatorymediators |