Comparison of EM-seq and PBAT methylome library methods for low-input DNA

Comparison of EM-seq and PBAT methylome library methods for low-input DNA

DNA methylation is the most studied epigenetic mark involved in regulation of gene expression. For low input samples, a limited number of methods for quantifying DNA methylation genome-wide has been evaluated. Here, we compared a series of input DNA amounts (1–10ng) from two methylome library prepar...

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Bibliographic Details
Main Authors: Yanan Han, Galina Yurevna Zheleznyakova, Yanara Marincevic-Zuniga, Majid Pahlevan Kakhki, Amanda Raine, Maria Needhamsen, Maja Jagodic
Format: Article
Language:English
Published: Taylor & Francis Group 2022-10-01
Series:Epigenetics
Subjects:
low input dna
methylome
em-seq
pbat
Online Access:http://dx.doi.org/10.1080/15592294.2021.1997406

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