Quantitative Structure Activity Relationship (QSAR) and Molecular Docking Study of Some Pyrrolones Antimalarial Agents against Plasmodium Falciparum

The increase in multidrug resistance malaria cases necessitates the need to search for new cost effective drugs. QSAR and molecular docking studies were performed on a data set of forty nine Pyrrolones antimalarial agents against Plasmodium falciparum. Forty two molecules were used as training set a...

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Bibliographic Details
Main Authors: Zaharaddeen Shehu, Adamu Uzairu, Balarabe Sagagi
Format: Article
Language:English
Published: Turkish Chemical Society 2018-01-01
Series:Journal of the Turkish Chemical Society, Section A: Chemistry
Subjects:
Online Access:http://dergipark.gov.tr/jotcsa/issue/33408/346661