Development of Liposome containing sodium deoxycholate to enhance oral bioavailability of itraconazole

Development of Liposome containing sodium deoxycholate to enhance oral bioavailability of itraconazole

The aim of this study was to enhance oral bioavailability of itraconazole (ITZ) by developing Liposome containing sodium deoxycholate (ITZ-Lip-NaDC). The liposome, consisting of egg yolk lecithin and sodium deoxycholate, was prepared by thin-film dispersion method. Differential Scanning Calorimetry...

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Bibliographic Details
Main Authors: Zhenbao Li, Meiyu Zhang, Chang Liu, Shiwei Zhou, Wenjuan Zhang, Tianyang Wang, Mei Zhou, Xiaohong Liu, Yongjun Wang, Yinghua Sun, Jin Sun
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Itraconazole
ITZ-Lip-NaDC
Dissolution
Intestinal infusion
Oral bioavailability
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616300563

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http://www.sciencedirect.com/science/article/pii/S1818087616300563

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