High-fiber-diet-related metabolites improve neurodegenerative symptoms in patients with obesity with diabetes mellitus by modulating the hippocampal–hypothalamic endocrine axis

High-fiber-diet-related metabolites improve neurodegenerative symptoms in patients with obesity with diabetes mellitus by modulating the hippocampal–hypothalamic endocrine axis

ObjectiveThrough transcriptomic and metabolomic analyses, this study examined the role of high-fiber diet in obesity complicated by diabetes and neurodegenerative symptoms.MethodThe expression matrix of high-fiber-diet-related metabolites, blood methylation profile associated with pre-symptomatic de...

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Bibliographic Details
Main Authors:	Ning Luo, Yuejie Guo, Lihua Peng, Fangli Deng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Neurology
Subjects:	high-fiber diet neurodegenerative diseases obesity neurovascular SPEG AD
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2022.1026904/full

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