SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice.

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice.

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The COVID-19 pandemic has been fueled by SARS-CoV-2 novel variants of concern (VOC) that have increased transmissibility, receptor binding affinity, and other properties that enhance disease. The goal of this study is to characterize unique pathogenesis of the Delta VOC strain in the K18-hACE2-mouse...

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Bibliographic Details
Main Authors: Katherine S Lee, Ting Y Wong, Brynnan P Russ, Alexander M Horspool, Olivia A Miller, Nathaniel A Rader, Jerome P Givi, Michael T Winters, Zeriel Y A Wong, Holly A Cyphert, James Denvir, Peter Stoilov, Mariette Barbier, Nadia R Roan, Md Shahrier Amin, Ivan Martinez, Justin R Bevere, F Heath Damron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0273430

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