Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case study
Adipose tissue is widely recognized as an abundant and accessible human tissue that serves as a source of cells and extracellular matrix scaffolds for regenerative surgical applications. Increasingly, orthopedic surgeons are turning to adipose tissue as a resource in their treatment of osteoarthriti...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Bone Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352187222004351 |
| _version_ | 1811178568259993600 |
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| author | Trivia Frazier Keith March Jaime R. Garza Bruce A. Bunnell Kevin F. Darr Emma Rogers Katie Hamel Jeffrey M. Gimble |
| author_facet | Trivia Frazier Keith March Jaime R. Garza Bruce A. Bunnell Kevin F. Darr Emma Rogers Katie Hamel Jeffrey M. Gimble |
| author_sort | Trivia Frazier |
| collection | DOAJ |
| description | Adipose tissue is widely recognized as an abundant and accessible human tissue that serves as a source of cells and extracellular matrix scaffolds for regenerative surgical applications. Increasingly, orthopedic surgeons are turning to adipose tissue as a resource in their treatment of osteoarthritis and related conditions. In the U.S., the regulatory landscape governing the orthopedic surgical utilization of autologous and allogeneic adipose tissue remains complex. This manuscript reviews the Food and Drug Administration's nomenclature and guidance regarding adipose tissue products. Additionally, it surveys recent pre-clinical and clinical trial literature relating to the application of adipose-derived cells and tissues in the treatment of osteoarthritis. |
| first_indexed | 2024-04-11T06:21:41Z |
| format | Article |
| id | doaj.art-453ae2ea84ca43f5b2901620ddad628f |
| institution | Directory Open Access Journal |
| issn | 2352-1872 |
| language | English |
| last_indexed | 2024-04-11T06:21:41Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Bone Reports |
| spelling | doaj.art-453ae2ea84ca43f5b2901620ddad628f2022-12-22T04:40:33ZengElsevierBone Reports2352-18722022-12-0117101601Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case studyTrivia Frazier0Keith March1Jaime R. Garza2Bruce A. Bunnell3Kevin F. Darr4Emma Rogers5Katie Hamel6Jeffrey M. Gimble7Obatala Sciences, New Orleans, LA, United States of America; Tulane University, New Orleans, LA, United States of AmericaUniversity of Florida, Gainesville, FL, United States of AmericaTulane University, New Orleans, LA, United States of America; University of Texas Health Sciences Center - San Antonio, San Antonio, TX, United States of AmericaUniversity of North Texas Health Science Center, Ft. Worth, TX, United States of AmericaCovington Orthopedics Sports Medicine Institute, Covington, LA, United States of AmericaObatala Sciences, New Orleans, LA, United States of AmericaObatala Sciences, New Orleans, LA, United States of AmericaObatala Sciences, New Orleans, LA, United States of America; Tulane University, New Orleans, LA, United States of America; Corresponding author at: Obatala Sciences, New Orleans, LA, United States of America.Adipose tissue is widely recognized as an abundant and accessible human tissue that serves as a source of cells and extracellular matrix scaffolds for regenerative surgical applications. Increasingly, orthopedic surgeons are turning to adipose tissue as a resource in their treatment of osteoarthritis and related conditions. In the U.S., the regulatory landscape governing the orthopedic surgical utilization of autologous and allogeneic adipose tissue remains complex. This manuscript reviews the Food and Drug Administration's nomenclature and guidance regarding adipose tissue products. Additionally, it surveys recent pre-clinical and clinical trial literature relating to the application of adipose-derived cells and tissues in the treatment of osteoarthritis.http://www.sciencedirect.com/science/article/pii/S2352187222004351AdiposeMicrofragmented fatOsteoarthritisRegulatory agencyRegenerative medicineStromal/stem cells |
| spellingShingle | Trivia Frazier Keith March Jaime R. Garza Bruce A. Bunnell Kevin F. Darr Emma Rogers Katie Hamel Jeffrey M. Gimble Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case study Bone Reports Adipose Microfragmented fat Osteoarthritis Regulatory agency Regenerative medicine Stromal/stem cells |
| title | Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case study |
| title_full | Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case study |
| title_fullStr | Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case study |
| title_full_unstemmed | Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case study |
| title_short | Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case study |
| title_sort | non homologous use of adipose derived cell and tissue therapies osteoarthritis as a case study |
| topic | Adipose Microfragmented fat Osteoarthritis Regulatory agency Regenerative medicine Stromal/stem cells |
| url | http://www.sciencedirect.com/science/article/pii/S2352187222004351 |
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