Testicular sperm retrieval at the time of bilateral radical orchiectomy

A new indication for testicular tissue cryopreservation is discussed here. We evaluate the feasibility of testicular sperm extraction during bilateral orchiectomy for testicular cancer. A 26-year-old man with a history of right orchidopexy presented with primary infertility. Tests revealed left vari...

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Main Authors: Nassir Anmar, Grantmyre John
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Urology Annals
Subjects:
Online Access:http://www.urologyannals.com/article.asp?issn=0974-7796;year=2009;volume=1;issue=1;spage=22;epage=24;aulast=Nassir
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author Nassir Anmar
Grantmyre John
author_facet Nassir Anmar
Grantmyre John
author_sort Nassir Anmar
collection DOAJ
description A new indication for testicular tissue cryopreservation is discussed here. We evaluate the feasibility of testicular sperm extraction during bilateral orchiectomy for testicular cancer. A 26-year-old man with a history of right orchidopexy presented with primary infertility. Tests revealed left varicocele and oligospermia. He underwent varicocelectomy but was lost to follow-up. Nine months later, he presented with right-sided solid testicular swelling. Ultrasound examination confirmed the finding of possible neoplasm and revealed contralateral intratesticular lesion. Since the patient turned azoospermic, no semen sample could be cryopreserved. Permanent histopathological sections revealed bilateral classical seminomas. On processing the fresh healthy looking specimen, normal-looking viable sperm were obtained. Future attempts at <i> in-vitro</i> fertilization with intracytoplasmic sperm injection should be possible. This method has been described in metachronous testicular cancer, but to our knowledge, we are the first to use it in synchronous bilateral testicular tumors.
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spelling doaj.art-453b1cf709704211bf189cfcb5bf5e022022-12-21T18:43:16ZengWolters Kluwer Medknow PublicationsUrology Annals0974-77960974-78342009-01-01112224Testicular sperm retrieval at the time of bilateral radical orchiectomyNassir AnmarGrantmyre JohnA new indication for testicular tissue cryopreservation is discussed here. We evaluate the feasibility of testicular sperm extraction during bilateral orchiectomy for testicular cancer. A 26-year-old man with a history of right orchidopexy presented with primary infertility. Tests revealed left varicocele and oligospermia. He underwent varicocelectomy but was lost to follow-up. Nine months later, he presented with right-sided solid testicular swelling. Ultrasound examination confirmed the finding of possible neoplasm and revealed contralateral intratesticular lesion. Since the patient turned azoospermic, no semen sample could be cryopreserved. Permanent histopathological sections revealed bilateral classical seminomas. On processing the fresh healthy looking specimen, normal-looking viable sperm were obtained. Future attempts at <i> in-vitro</i> fertilization with intracytoplasmic sperm injection should be possible. This method has been described in metachronous testicular cancer, but to our knowledge, we are the first to use it in synchronous bilateral testicular tumors.http://www.urologyannals.com/article.asp?issn=0974-7796;year=2009;volume=1;issue=1;spage=22;epage=24;aulast=NassirAzoospermiabilateral seminomamale infertilityorchidopexysynchronous testicular cancerTESE
spellingShingle Nassir Anmar
Grantmyre John
Testicular sperm retrieval at the time of bilateral radical orchiectomy
Urology Annals
Azoospermia
bilateral seminoma
male infertility
orchidopexy
synchronous testicular cancer
TESE
title Testicular sperm retrieval at the time of bilateral radical orchiectomy
title_full Testicular sperm retrieval at the time of bilateral radical orchiectomy
title_fullStr Testicular sperm retrieval at the time of bilateral radical orchiectomy
title_full_unstemmed Testicular sperm retrieval at the time of bilateral radical orchiectomy
title_short Testicular sperm retrieval at the time of bilateral radical orchiectomy
title_sort testicular sperm retrieval at the time of bilateral radical orchiectomy
topic Azoospermia
bilateral seminoma
male infertility
orchidopexy
synchronous testicular cancer
TESE
url http://www.urologyannals.com/article.asp?issn=0974-7796;year=2009;volume=1;issue=1;spage=22;epage=24;aulast=Nassir
work_keys_str_mv AT nassiranmar testicularspermretrievalatthetimeofbilateralradicalorchiectomy
AT grantmyrejohn testicularspermretrievalatthetimeofbilateralradicalorchiectomy