Genomic and phenotypic analyses suggest moderate fitness differences among Zika virus lineages.

Genomic and phenotypic analyses suggest moderate fitness differences among Zika virus lineages.

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RNA viruses have short generation times and high mutation rates, allowing them to undergo rapid molecular evolution during epidemics. However, the extent of RNA virus phenotypic evolution within epidemics and the resulting effects on fitness and virulence remain mostly unknown. Here, we screened the...

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Bibliographic Details
Main Authors: Glenn Oliveira, Chantal B F Vogels, Ashley Zolfaghari, Sharada Saraf, Raphaelle Klitting, James Weger-Lucarelli, Karla P Leon, Carlos O Ontiveros, Rimjhim Agarwal, Konstantin A Tsetsarkin, Eva Harris, Gregory D Ebel, Shirlee Wohl, Nathan D Grubaugh, Kristian G Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011055

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