Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma

Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma

Abstract Background The plasticity of cancer stem cells (CSCs)/tumor-initiating cells (T-ICs) suggests that multiple CSC/T-IC subpopulations exist within a tumor and that multiple oncogenic pathways collaborate to maintain the CSC/T-IC state. Here, we aimed to identify potential therapeutic targets...

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Bibliographic Details
Main Authors: Aibin Liu, Jinrong Zhu, Geyan Wu, Lixue Cao, Zhanyao Tan, Shuxia Zhang, Lili Jiang, Jueheng Wu, Mengfeng Li, Libing Song, Jun Li
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Molecular Cancer
Subjects:
miR-455-3p
Chemoresistance
Esophageal squamous cell carcinoma
OncomiR
Online Access:http://link.springer.com/article/10.1186/s12943-017-0669-9

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