Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse

Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse

Abstract Background Catastrophic chromosomal event known as chromothripsis was proven to be a significant hallmark of poor prognosis in several cancer diseases. While this phenomenon is very rare in among multiple myeloma (MM) patients, its presence in karyotype is associated with very poor prognosi...

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Bibliographic Details
Main Authors: Jan Smetana, Jan Oppelt, Martin Štork, Luděk Pour, Petr Kuglík
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Molecular Cytogenetics
Subjects:
Multiple myeloma
Chromothripsis
Array-CGH
NGS
Mutation screening
Online Access:http://link.springer.com/article/10.1186/s13039-018-0357-5

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