Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN)
BackgroundMost of the studies on cystic fibrosis (CF) focused on SARS-CoV-2 prevalence and suggested a low incidence of infection in this population. We aimed to assess the impact of the pandemic and related lockdown measures implemented in May 2020 in response to the first wave of SARS-CoV-2 infect...
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.978627/full |
| _version_ | 1798015023464841216 |
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| author | Nadia Oubaya Nadia Oubaya Thibaud Pombet Thibaud Pombet Celine Delestrain Celine Delestrain Celine Delestrain Celine Delestrain Natascha Remus Natascha Remus Benoit Douvry Benoit Douvry Dominique Grenet Harriet Corvol Harriet Corvol Guillaume Thouvenin Virginie Prulière-Escabasse Virginie Prulière-Escabasse Virginie Prulière-Escabasse Hakima Mounir Dominique Argoud Cédric Fretigne Laurence Costes Marie-Pierre Mackiewicz Camille Jung Laitissia Ahamada Sophie Lanone Sophie Lanone Sophie Lanone Bernard Maitre Bernard Maitre Bernard Maitre Bernard Maitre Anne-Cécile Bégot Ralph Epaud Ralph Epaud Ralph Epaud Ralph Epaud |
| author_facet | Nadia Oubaya Nadia Oubaya Thibaud Pombet Thibaud Pombet Celine Delestrain Celine Delestrain Celine Delestrain Celine Delestrain Natascha Remus Natascha Remus Benoit Douvry Benoit Douvry Dominique Grenet Harriet Corvol Harriet Corvol Guillaume Thouvenin Virginie Prulière-Escabasse Virginie Prulière-Escabasse Virginie Prulière-Escabasse Hakima Mounir Dominique Argoud Cédric Fretigne Laurence Costes Marie-Pierre Mackiewicz Camille Jung Laitissia Ahamada Sophie Lanone Sophie Lanone Sophie Lanone Bernard Maitre Bernard Maitre Bernard Maitre Bernard Maitre Anne-Cécile Bégot Ralph Epaud Ralph Epaud Ralph Epaud Ralph Epaud |
| author_sort | Nadia Oubaya |
| collection | DOAJ |
| description | BackgroundMost of the studies on cystic fibrosis (CF) focused on SARS-CoV-2 prevalence and suggested a low incidence of infection in this population. We aimed to assess the impact of the pandemic and related lockdown measures implemented in May 2020 in response to the first wave of SARS-CoV-2 infection on healthcare access, health, and behavior in CF patients.MethodsA national questionnaire opened online from May 15th, 2020 to June 11th, 2020 was completed by 751 CF-patients, aged 14 years and over. It comprised questions about access to healthcare, anxiety and depression, smoking, alcohol, drug and psychotropic drug consumption, adherence to CF treatment, and constraints. A semi-structured comprehensive interview was performed no later than 1 month after the end of the lockdown in 16 CF-patients.ResultsThe mean age of the population was 28.0 [interquartile range (IQR) 20.0–37.0] years old. More than 75% of in-person consultations scheduled during the lockdown were canceled. Alternatively, 27% were postponed, and telehealth consultations were proposed and accepted in almost 40% of cases. More than 75% of the scheduled physiotherapy sessions were canceled and replaced mainly by self-drainage. Annual follow-up clinic visits were consistently postponed whereas required hospitalizations at CF centers for exacerbation were maintained in most cases. While 43.2% CF-patients had signs of anxiety, 51.0% presented symptoms of depression, both associated with increased use of psychotic medications and inversely correlated to COVID-19 prevalence. Among the lower and lower middle classes, very little medical information was obtained or requested by the patient, participation to sports or other activities was low, while excessive home confinement and isolation were more frequent. In contrast, in the upper middle and upper classes, individuals solicitated help to their CF centre, had more physical activities, and maintained contact with friends or families.ConclusionThe first lockdown in France had only minimal impact on the management care of CF-patients but was associated with increased symptoms of anxiety and depression, together with behavioral changes that varied with social class.Trial registrationNCT04463628. |
| first_indexed | 2024-04-11T15:27:45Z |
| format | Article |
| id | doaj.art-4540d61934d84dbb8a1b5991917820e4 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-11T15:27:45Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-4540d61934d84dbb8a1b5991917820e42022-12-22T04:16:13ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-11-011010.3389/fpubh.2022.978627978627Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN)Nadia Oubaya0Nadia Oubaya1Thibaud Pombet2Thibaud Pombet3Celine Delestrain4Celine Delestrain5Celine Delestrain6Celine Delestrain7Natascha Remus8Natascha Remus9Benoit Douvry10Benoit Douvry11Dominique Grenet12Harriet Corvol13Harriet Corvol14Guillaume Thouvenin15Virginie Prulière-Escabasse16Virginie Prulière-Escabasse17Virginie Prulière-Escabasse18Hakima Mounir19Dominique Argoud20Cédric Fretigne21Laurence Costes22Marie-Pierre Mackiewicz23Camille Jung24Laitissia Ahamada25Sophie Lanone26Sophie Lanone27Sophie Lanone28Bernard Maitre29Bernard Maitre30Bernard Maitre31Bernard Maitre32Anne-Cécile Bégot33Ralph Epaud34Ralph Epaud35Ralph Epaud36Ralph Epaud37Department of Public Health, AP-HP, Hôpitaux Henri-Mondor, Créteil, FranceUniversity Paris Est Créteil, INSERM, IMRB, Créteil, FranceLaboratoire Interdisciplinaire de Recherche sur les Transformations des Pratiques Éducatives et des Pratiques Sociales (LIRTES)-EA7313, Université Paris-Est Créteil Val-de-Marne, Créteil, FranceFaculté d'Éducation et de Formation, Institut Catholique de Paris (ICP), Paris, FranceUniversity Paris Est Créteil, INSERM, IMRB, Créteil, FranceCentre Hospitalier Intercommunal de Créteil, Service de Pédiatrie Générale, Créteil, FranceCentre des Maladies Respiratoires Rares (RESPIRARE®), CRCM, Créteil, FranceFédérations Hospitalo-Universitaires (FHU) Role of SENEscence in Chronic Diseases (SENEC), Créteil, FranceCentre Hospitalier Intercommunal de Créteil, Service de Pédiatrie Générale, Créteil, FranceCentre des Maladies Respiratoires Rares (RESPIRARE®), CRCM, Créteil, FranceCentre des Maladies Respiratoires Rares (RESPIRARE®), CRCM, Créteil, FranceCentre Hospitalier Intercommunal de Créteil, Service de Pneumologie, Créteil, FranceService de Pneumologie, CRCM-Centre de Transplantation Pulmonaire, Hôpital Foch, Suresnes, France0Assistance Publique-Hôpitaux de Paris, Hôpital Trousseau, Pediatric Pulmonary Department, Paris, France1Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre de Recherche Saint Antoine, Paris, France0Assistance Publique-Hôpitaux de Paris, Hôpital Trousseau, Pediatric Pulmonary Department, Paris, FranceUniversity Paris Est Créteil, INSERM, IMRB, Créteil, FranceCentre des Maladies Respiratoires Rares (RESPIRARE®), CRCM, Créteil, France2Centre Hospitalier Intercommunal de Créteil, Service d'ORL, Créteil, FranceLaboratoire Interdisciplinaire de Recherche sur les Transformations des Pratiques Éducatives et des Pratiques Sociales (LIRTES)-EA7313, Université Paris-Est Créteil Val-de-Marne, Créteil, FranceLaboratoire Interdisciplinaire de Recherche sur les Transformations des Pratiques Éducatives et des Pratiques Sociales (LIRTES)-EA7313, Université Paris-Est Créteil Val-de-Marne, Créteil, FranceLaboratoire Interdisciplinaire de Recherche sur les Transformations des Pratiques Éducatives et des Pratiques Sociales (LIRTES)-EA7313, Université Paris-Est Créteil Val-de-Marne, Créteil, FranceLaboratoire Interdisciplinaire de Recherche sur les Transformations des Pratiques Éducatives et des Pratiques Sociales (LIRTES)-EA7313, Université Paris-Est Créteil Val-de-Marne, Créteil, FranceLaboratoire Interdisciplinaire de Recherche sur les Transformations des Pratiques Éducatives et des Pratiques Sociales (LIRTES)-EA7313, Université Paris-Est Créteil Val-de-Marne, Créteil, France3Clinical Research Centre, Intercommunal Hospital of Créteil, Créteil, France3Clinical Research Centre, Intercommunal Hospital of Créteil, Créteil, FranceUniversity Paris Est Créteil, INSERM, IMRB, Créteil, FranceCentre des Maladies Respiratoires Rares (RESPIRARE®), CRCM, Créteil, FranceFédérations Hospitalo-Universitaires (FHU) Role of SENEscence in Chronic Diseases (SENEC), Créteil, FranceUniversity Paris Est Créteil, INSERM, IMRB, Créteil, FranceCentre des Maladies Respiratoires Rares (RESPIRARE®), CRCM, Créteil, FranceFédérations Hospitalo-Universitaires (FHU) Role of SENEscence in Chronic Diseases (SENEC), Créteil, FranceCentre Hospitalier Intercommunal de Créteil, Service de Pneumologie, Créteil, FranceLaboratoire Interdisciplinaire de Recherche sur les Transformations des Pratiques Éducatives et des Pratiques Sociales (LIRTES)-EA7313, Université Paris-Est Créteil Val-de-Marne, Créteil, FranceUniversity Paris Est Créteil, INSERM, IMRB, Créteil, FranceCentre Hospitalier Intercommunal de Créteil, Service de Pédiatrie Générale, Créteil, FranceCentre des Maladies Respiratoires Rares (RESPIRARE®), CRCM, Créteil, FranceFédérations Hospitalo-Universitaires (FHU) Role of SENEscence in Chronic Diseases (SENEC), Créteil, FranceBackgroundMost of the studies on cystic fibrosis (CF) focused on SARS-CoV-2 prevalence and suggested a low incidence of infection in this population. We aimed to assess the impact of the pandemic and related lockdown measures implemented in May 2020 in response to the first wave of SARS-CoV-2 infection on healthcare access, health, and behavior in CF patients.MethodsA national questionnaire opened online from May 15th, 2020 to June 11th, 2020 was completed by 751 CF-patients, aged 14 years and over. It comprised questions about access to healthcare, anxiety and depression, smoking, alcohol, drug and psychotropic drug consumption, adherence to CF treatment, and constraints. A semi-structured comprehensive interview was performed no later than 1 month after the end of the lockdown in 16 CF-patients.ResultsThe mean age of the population was 28.0 [interquartile range (IQR) 20.0–37.0] years old. More than 75% of in-person consultations scheduled during the lockdown were canceled. Alternatively, 27% were postponed, and telehealth consultations were proposed and accepted in almost 40% of cases. More than 75% of the scheduled physiotherapy sessions were canceled and replaced mainly by self-drainage. Annual follow-up clinic visits were consistently postponed whereas required hospitalizations at CF centers for exacerbation were maintained in most cases. While 43.2% CF-patients had signs of anxiety, 51.0% presented symptoms of depression, both associated with increased use of psychotic medications and inversely correlated to COVID-19 prevalence. Among the lower and lower middle classes, very little medical information was obtained or requested by the patient, participation to sports or other activities was low, while excessive home confinement and isolation were more frequent. In contrast, in the upper middle and upper classes, individuals solicitated help to their CF centre, had more physical activities, and maintained contact with friends or families.ConclusionThe first lockdown in France had only minimal impact on the management care of CF-patients but was associated with increased symptoms of anxiety and depression, together with behavioral changes that varied with social class.Trial registrationNCT04463628.https://www.frontiersin.org/articles/10.3389/fpubh.2022.978627/fullcystic fibrosishealthcareCOVID-19lockdownanxiety |
| spellingShingle | Nadia Oubaya Nadia Oubaya Thibaud Pombet Thibaud Pombet Celine Delestrain Celine Delestrain Celine Delestrain Celine Delestrain Natascha Remus Natascha Remus Benoit Douvry Benoit Douvry Dominique Grenet Harriet Corvol Harriet Corvol Guillaume Thouvenin Virginie Prulière-Escabasse Virginie Prulière-Escabasse Virginie Prulière-Escabasse Hakima Mounir Dominique Argoud Cédric Fretigne Laurence Costes Marie-Pierre Mackiewicz Camille Jung Laitissia Ahamada Sophie Lanone Sophie Lanone Sophie Lanone Bernard Maitre Bernard Maitre Bernard Maitre Bernard Maitre Anne-Cécile Bégot Ralph Epaud Ralph Epaud Ralph Epaud Ralph Epaud Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN) Frontiers in Public Health cystic fibrosis healthcare COVID-19 lockdown anxiety |
| title | Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN) |
| title_full | Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN) |
| title_fullStr | Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN) |
| title_full_unstemmed | Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN) |
| title_short | Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN) |
| title_sort | impact of the covid 19 pandemic and associated lockdown measures on the management health and behavior of the cystic fibrosis population in france during 2020 muconfin |
| topic | cystic fibrosis healthcare COVID-19 lockdown anxiety |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.978627/full |
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