Fatigue and activity-dependent conduction block in neuromuscular disorders

Fatigue and activity-dependent conduction block in neuromuscular disorders

Objective: Fatigue is a major disabling problem in patients with neuromuscular disorders. Both nerve demyelination and increased axonal branching associated with collateral sprouting reduce the safety factor for impulse transmission and could cause activity-dependent hyperpolarization and conduction...

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Bibliographic Details
Main Authors:	Atsuko Tsuneyama, Kazumoto Shibuya, Sonoko Misawa, Yo-ichi Suzuki, Tomoki Suichi, Yuta Kojima, Keigo Nakamura, Hiroki Kano, Mario J. Prado, Satoshi Kuwabara
Format:	Article
Language:	English
Published:	Elsevier 2022-01-01
Series:	Clinical Neurophysiology Practice
Subjects:	Fatigue Chronic inflammatory demyelinating polyneuropathy Spinal and bulbar muscular atrophy Activity-dependent hyperpolarization and conduction block
Online Access:	http://www.sciencedirect.com/science/article/pii/S2467981X22000105

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