Wide field-of-view Fourier Ptychography microscopy based on Fresnel propagation scheme

Fourier ptychographic microscopy (FPM) is a computational imaging method that gives a significantly increased space-bandwidth product, in practice high resolution combined with a wide field of view. In this article, we propose an improved Fourier Ptychography algorithm based on Fresnel wave propagat...

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Main Authors: Mojde Hasanzade, Dag Werner Breiby, Muhammad Nadeem Akram
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Results in Optics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666950122000499
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author Mojde Hasanzade
Dag Werner Breiby
Muhammad Nadeem Akram
author_facet Mojde Hasanzade
Dag Werner Breiby
Muhammad Nadeem Akram
author_sort Mojde Hasanzade
collection DOAJ
description Fourier ptychographic microscopy (FPM) is a computational imaging method that gives a significantly increased space-bandwidth product, in practice high resolution combined with a wide field of view. In this article, we propose an improved Fourier Ptychography algorithm based on Fresnel wave propagation integral for wide field-of-view coherent imaging while correcting for the misalignment of the illuminating LED board and calibration of system parameters. In addition, the wave emanating from the LEDs is taken to be parabolic instead of plane wave as done by others. The advantage of this scheme is that it enables to simulate the transition regions between bright and dark field in wide image patches, and hence this feature can be used to estimate the LED misalignment as well as the distortion of the imaging lens. Experimental results are presented for a USAF resolution target and a biological sample for on-axis and off-axis image patches over a wide sample area showing excellent performance of this scheme when compared to the traditional Fraunhofer-model based Fourier Ptychography algorithm. The article summarizes with high technical detail our experiences with developing and implementing improved FPM methods and will hopefully assist other scientists entering this scientific field.
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spelling doaj.art-4547efcec5aa44d9a1a43837322809432022-12-22T03:00:03ZengElsevierResults in Optics2666-95012022-08-018100259Wide field-of-view Fourier Ptychography microscopy based on Fresnel propagation schemeMojde Hasanzade0Dag Werner Breiby1Muhammad Nadeem Akram2Department of Microsystems, University of South-Eastern Norway, Raveien 215, Borre, Norway; Correspondence to: University of South-Eastern Norway (USN), NorwayDepartment of Microsystems, University of South-Eastern Norway, Raveien 215, Borre, Norway; PoreLab, Department of Physics, Norwegian University of Science and Technology(NTNU), Høgskoleringen 5, 7491 Trondheim, NorwayDepartment of Microsystems, University of South-Eastern Norway, Raveien 215, Borre, Norway; Correspondence to: University of South-Eastern Norway (USN), NorwayFourier ptychographic microscopy (FPM) is a computational imaging method that gives a significantly increased space-bandwidth product, in practice high resolution combined with a wide field of view. In this article, we propose an improved Fourier Ptychography algorithm based on Fresnel wave propagation integral for wide field-of-view coherent imaging while correcting for the misalignment of the illuminating LED board and calibration of system parameters. In addition, the wave emanating from the LEDs is taken to be parabolic instead of plane wave as done by others. The advantage of this scheme is that it enables to simulate the transition regions between bright and dark field in wide image patches, and hence this feature can be used to estimate the LED misalignment as well as the distortion of the imaging lens. Experimental results are presented for a USAF resolution target and a biological sample for on-axis and off-axis image patches over a wide sample area showing excellent performance of this scheme when compared to the traditional Fraunhofer-model based Fourier Ptychography algorithm. The article summarizes with high technical detail our experiences with developing and implementing improved FPM methods and will hopefully assist other scientists entering this scientific field.http://www.sciencedirect.com/science/article/pii/S2666950122000499Fourier PtychographyFresnel propagationPhase retrieval
spellingShingle Mojde Hasanzade
Dag Werner Breiby
Muhammad Nadeem Akram
Wide field-of-view Fourier Ptychography microscopy based on Fresnel propagation scheme
Results in Optics
Fourier Ptychography
Fresnel propagation
Phase retrieval
title Wide field-of-view Fourier Ptychography microscopy based on Fresnel propagation scheme
title_full Wide field-of-view Fourier Ptychography microscopy based on Fresnel propagation scheme
title_fullStr Wide field-of-view Fourier Ptychography microscopy based on Fresnel propagation scheme
title_full_unstemmed Wide field-of-view Fourier Ptychography microscopy based on Fresnel propagation scheme
title_short Wide field-of-view Fourier Ptychography microscopy based on Fresnel propagation scheme
title_sort wide field of view fourier ptychography microscopy based on fresnel propagation scheme
topic Fourier Ptychography
Fresnel propagation
Phase retrieval
url http://www.sciencedirect.com/science/article/pii/S2666950122000499
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AT dagwernerbreiby widefieldofviewfourierptychographymicroscopybasedonfresnelpropagationscheme
AT muhammadnadeemakram widefieldofviewfourierptychographymicroscopybasedonfresnelpropagationscheme