Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer

Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer

Abstract Triple-negative breast cancer (TNBC) is characterized by its aggressiveness and resistance to cancer-specific transcriptome alterations. Alternative splicing (AS) is a major contributor to the diversification of cancer-specific transcriptomes. The TNBC transcriptome landscape is characteriz...

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Bibliographic Details
Main Authors: Meenakshi Sudhakaran, Tatiana García Navarrete, Katherine Mejía-Guerra, Eric Mukundi, Timothy D. Eubank, Erich Grotewold, Daniel Arango, Andrea I. Doseff
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06342-6

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