Severe allergic reaction to human insulin in the patient with diabetic ketoacidosis
Diabetic ketoacidosis (DKA) is an acute and major life-threatening complication of diabetes mellitus. Fluid resuscitation, insulin therapy, and electrolyte replacement are essential for DKA treatment. Rarely, life threatening allergic reactions might develop in a patient treated with insulin. If ana...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-03-01
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| Series: | Turkish Journal of Emergency Medicine |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452247317301371 |
| _version_ | 1818912302349418496 |
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| author | Nese Colak Oray Basak Bayram Emel Altintas Semra Sivrikaya Yusuf Savran |
| author_facet | Nese Colak Oray Basak Bayram Emel Altintas Semra Sivrikaya Yusuf Savran |
| author_sort | Nese Colak Oray |
| collection | DOAJ |
| description | Diabetic ketoacidosis (DKA) is an acute and major life-threatening complication of diabetes mellitus. Fluid resuscitation, insulin therapy, and electrolyte replacement are essential for DKA treatment. Rarely, life threatening allergic reactions might develop in a patient treated with insulin. If anaphylaxis develops after insulin, the DKA treatment options are restricted. A limited number of case reports have been reported in patients with severe anaphylactic reactions to human insulin who were then treated with synthetic insulin analogues. We present a case of a 45-year-old male patient with allergic reactions to human insulin. The patient was successfully treated with insulin aspart and hemodialysis. Keywords: Diabetic ketoacidosis, Regular insulin, Allergic reaction, Emergency treatment, Insulin aspart |
| first_indexed | 2024-12-19T23:12:26Z |
| format | Article |
| id | doaj.art-4551619670f14a86bb4e205e7af5f86d |
| institution | Directory Open Access Journal |
| issn | 2452-2473 |
| language | English |
| last_indexed | 2024-12-19T23:12:26Z |
| publishDate | 2018-03-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Turkish Journal of Emergency Medicine |
| spelling | doaj.art-4551619670f14a86bb4e205e7af5f86d2022-12-21T20:02:10ZengWolters Kluwer Medknow PublicationsTurkish Journal of Emergency Medicine2452-24732018-03-011814041Severe allergic reaction to human insulin in the patient with diabetic ketoacidosisNese Colak Oray0Basak Bayram1Emel Altintas2Semra Sivrikaya3Yusuf Savran4Dokuz Eylul University, Faculty of Medicine, Department of Emergency Medicine, Balcova, 35340, Izmir, Turkey; Corresponding author.Dokuz Eylul University, Faculty of Medicine, Department of Emergency Medicine, Balcova, 35340, Izmir, TurkeyAdiyaman University, Training and Research Hospital, Department of Emergency Medicine, Adiyaman, TurkeyArtvin State Hospital, Department of Emergency Medicine, Artvin, TurkeyDokuz Eylul University, Faculty of Medicine, Department of Internal Medicine, Balcova, 35340, Izmir, TurkeyDiabetic ketoacidosis (DKA) is an acute and major life-threatening complication of diabetes mellitus. Fluid resuscitation, insulin therapy, and electrolyte replacement are essential for DKA treatment. Rarely, life threatening allergic reactions might develop in a patient treated with insulin. If anaphylaxis develops after insulin, the DKA treatment options are restricted. A limited number of case reports have been reported in patients with severe anaphylactic reactions to human insulin who were then treated with synthetic insulin analogues. We present a case of a 45-year-old male patient with allergic reactions to human insulin. The patient was successfully treated with insulin aspart and hemodialysis. Keywords: Diabetic ketoacidosis, Regular insulin, Allergic reaction, Emergency treatment, Insulin asparthttp://www.sciencedirect.com/science/article/pii/S2452247317301371 |
| spellingShingle | Nese Colak Oray Basak Bayram Emel Altintas Semra Sivrikaya Yusuf Savran Severe allergic reaction to human insulin in the patient with diabetic ketoacidosis Turkish Journal of Emergency Medicine |
| title | Severe allergic reaction to human insulin in the patient with diabetic ketoacidosis |
| title_full | Severe allergic reaction to human insulin in the patient with diabetic ketoacidosis |
| title_fullStr | Severe allergic reaction to human insulin in the patient with diabetic ketoacidosis |
| title_full_unstemmed | Severe allergic reaction to human insulin in the patient with diabetic ketoacidosis |
| title_short | Severe allergic reaction to human insulin in the patient with diabetic ketoacidosis |
| title_sort | severe allergic reaction to human insulin in the patient with diabetic ketoacidosis |
| url | http://www.sciencedirect.com/science/article/pii/S2452247317301371 |
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