Parallel evolution of linezolid-resistant Staphylococcus aureus in patients with cystic fibrosis

Parallel evolution of linezolid-resistant Staphylococcus aureus in patients with cystic fibrosis

ABSTRACT Linezolid is an antibiotic used to treat serious Staphylococcus aureus infections. Resistance to linezolid is considered rare but could emerge with repeated dosing. We recently reported widespread prescription of linezolid for a cohort of patients with cystic fibrosis (CF). The goals of thi...

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Bibliographic Details
Main Authors: Nicholas J. Pitcher, Andries Feder, Nicholas Bolden, Christian F. Zirbes, Anthony J. Pamatmat, Linda Boyken, Jared J. Hill, Alyssa R. Bartels, Andrew L. Thurman, Valerie C. Reeb, Harry S. Porterfield, Ahmed M. Moustafa, Paul J. Planet, Anthony J. Fischer
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Staphylococcus aureus
linezolid
MRSA
ribosomal RNA
hypermutation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02084-23

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