Spinal paraganglioma presenting as a lumbar canal stenosis – a rare case report
Paragangliomas arise from para ganglion cells. These are slow growing tumors (< 2 cm in 5 years) and are histologically benign (< 10% associated with lymphnode involvement or distant spread). Most contain secretory granules on electron microscopy (mostly epinephrine & norepinephrine, a...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Prathima Institute of Medical Sciences
2019-08-01
|
| Series: | Perspectives In Medical Research |
| Subjects: | |
| Online Access: | http://www.pimr.org.in/2019-vol7-issue-2/sanjeev_v2.PDF |
| Summary: | Paragangliomas arise from para ganglion cells. These
are slow growing tumors (< 2 cm in 5 years) and are
histologically benign (< 10% associated with lymphnode
involvement or distant spread). Most contain secretory
granules on electron microscopy (mostly epinephrine & norepinephrine, and these tumors may occasionally secrete these
catecholamines with risk of life-threatening hypertension and/
or cardiac arrhythmias). Carotid bifurcation most common site.
Spinal paragangliomas are very rare neuroendocrine tumors
often presenting with low back pain and radicular symptoms.
Radiographically spinal paragangliomas mimic more commonly
described tumors, such as ependymomas, schwannomas,
meningiomas, and even hemangiomas, but a "salt and pepper"
appearance related to a serpiginous vascular structure is
instructive. Indeed, the rarity of this tumor makes the diagnosis
rather challenging radiographically. We report a case of 55yrs
old female patient with clinical presentation like lumbar canal
stenosis on evalution found intra dural spinal canal tumor at
L3and L4 vertebra,suspected to be schwanomma radiologically.
After excision of the specimen and sent for histopathological
examination suggestive of ependymoma. After
immunohistochemistry study of tumor found to be
paraganglioma. |
|---|---|
| ISSN: | 2348-1447 2348-229X |