Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD

Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD

Summary: Protein post-translational modifications (PTMs) participate in important bioactive regulatory processes and therefore can help elucidate the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Here, we investigate the involvement of PTMs in ketogenic diet (KD)-improved fatty liver by...

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Bibliographic Details
Main Authors: Huanyi Cao, Qingxian Cai, Wanrong Guo, Qiao Su, Hancheng Qin, Tian Wang, Yingxin Xian, Longyi Zeng, Mengyin Cai, Haixia Guan, Sifan Chen, Hua Liang, Fen Xu
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003303

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