Control of cation permeation through the nicotinic receptor channel.

Control of cation permeation through the nicotinic receptor channel.

We used molecular dynamics (MD) simulations to explore the transport of single cations through the channel of the muscle nicotinic acetylcholine receptor (nAChR). Four MD simulations of 16 ns were performed at physiological and hyperpolarized membrane potentials, with and without restraints of the s...

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Bibliographic Details
Main Authors: Hai-Long Wang, Xiaolin Cheng, Palmer Taylor, J Andrew McCammon, Steven M Sine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2242826?pdf=render

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