Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water

Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water

Arabinonucleic acid (ANA) Watson-Crick base-pair with RNA/DNA and can evolve to display enzyme-like function. Here, the authors now identify a prebiotic pathway that yields the complete set of Watson-Crick base-pairing purine and pyrimidine ANA nucleosides.

Bibliographic Details
Main Authors: Samuel J. Roberts, Rafał Szabla, Zoe R. Todd, Shaun Stairs, Dejan-Krešimir Bučar, Jiří Šponer, Dimitar D. Sasselov, Matthew W. Powner
Format: Article
Language:English
Published: Nature Portfolio 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06374-z

Internet

https://doi.org/10.1038/s41467-018-06374-z

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