4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-1,2-dihydroquinoline-3-carboxamide

The title compound, C20H17F3N2O4, named tasquinimod, is a second-generation oral quinoline-3-carboxamide analogue, which is currently in phase III clinical trials for the treatment of metastatic prostate cancer. The quinoline unit is almost planar (r.m.s. deviation of fitted atoms = 0.0075 Å). The c...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Emmanuel S. Akinboye, Ray J. Butcher, Sema Ozturk Yildirim, John T. Isaacs
स्वरूप: लेख
भाषा:English
प्रकाशित: International Union of Crystallography 2014-03-01
श्रृंखला:Acta Crystallographica Section E
ऑनलाइन पहुंच:http://scripts.iucr.org/cgi-bin/paper?S1600536814003031