Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in Zebrafish

Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in Zebrafish

During the course of infection, Mycobacterium tuberculosis (Mtb) is exposed to diverse redox stresses that trigger metabolic and physiological changes. How these stressors are sensed and relayed to the Mtb transcriptional apparatus remains unclear. Here, we provide evidence that WhiB6 differentially...

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Bibliographic Details
Main Authors:	Zhenkang Chen, Yangbo Hu, Bridgette M. Cumming, Pei Lu, Lipeng Feng, Jiaoyu Deng, Adrie J.C. Steyn, Shiyun Chen
Format:	Article
Language:	English
Published:	Elsevier 2016-08-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124716310269

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