Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric Rhabdomyosarcoma
Rhabdomyosarcoma is the most common soft-tissue sarcoma of childhood. Despite clinical advances, subsets of these patients continue to suffer high morbidity and mortality rates associated with their disease. Following the European guidelines for <sup>18</sup>F-FDG PET and PET-CT imaging...
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| Format: | Article |
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MDPI AG
2020-12-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/10/12/1112 |
| _version_ | 1827699545025282048 |
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| author | Davide Donner Paola Feraco Linda Meneghello Barbara Rombi Lorena Picori Franca Chierichetti |
| author_facet | Davide Donner Paola Feraco Linda Meneghello Barbara Rombi Lorena Picori Franca Chierichetti |
| author_sort | Davide Donner |
| collection | DOAJ |
| description | Rhabdomyosarcoma is the most common soft-tissue sarcoma of childhood. Despite clinical advances, subsets of these patients continue to suffer high morbidity and mortality rates associated with their disease. Following the European guidelines for <sup>18</sup>F-FDG PET and PET-CT imaging in pediatric oncology, the routine use of <sup>18</sup>F-FDG PET-CT may be useful for patients affected by rhabdomyosarcoma, in staging, in the evaluation of response to therapy, and for restaging/detection of relapse. The European Pediatric Protocols are very old, and for staging and restaging, they recommend only radionuclide bone scan. The <sup>18</sup>F-FDG PET-CT exam is listed as an optional investigation prescribed according to local availability and local protocols in the investigations panel required at the end of the treatment. We present two cases highlighting the usefulness of <sup>18</sup>F-FDG PET-CT in managing pediatric patients affected by rhabdomyosarcoma, providing some bibliographic references. |
| first_indexed | 2024-03-10T13:52:09Z |
| format | Article |
| id | doaj.art-4560f6788c654243a33b1ad8822868b7 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T13:52:09Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-4560f6788c654243a33b1ad8822868b72023-11-21T01:58:40ZengMDPI AGDiagnostics2075-44182020-12-011012111210.3390/diagnostics10121112Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric RhabdomyosarcomaDavide Donner0Paola Feraco1Linda Meneghello2Barbara Rombi3Lorena Picori4Franca Chierichetti5Nuclear Medicine Unit, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38123 Trento, ItalyUnit of Neuroradiology, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38123 Trento, ItalyDepartment of Pediatrics, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38123 Trento, ItalyProton Therapy Center, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38123 Trento, ItalyNuclear Medicine Unit, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38123 Trento, ItalyNuclear Medicine Unit, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38123 Trento, ItalyRhabdomyosarcoma is the most common soft-tissue sarcoma of childhood. Despite clinical advances, subsets of these patients continue to suffer high morbidity and mortality rates associated with their disease. Following the European guidelines for <sup>18</sup>F-FDG PET and PET-CT imaging in pediatric oncology, the routine use of <sup>18</sup>F-FDG PET-CT may be useful for patients affected by rhabdomyosarcoma, in staging, in the evaluation of response to therapy, and for restaging/detection of relapse. The European Pediatric Protocols are very old, and for staging and restaging, they recommend only radionuclide bone scan. The <sup>18</sup>F-FDG PET-CT exam is listed as an optional investigation prescribed according to local availability and local protocols in the investigations panel required at the end of the treatment. We present two cases highlighting the usefulness of <sup>18</sup>F-FDG PET-CT in managing pediatric patients affected by rhabdomyosarcoma, providing some bibliographic references.https://www.mdpi.com/2075-4418/10/12/1112<sup>18</sup>F-FDG PET-CTrhabdomyosarcomapediatricstagingrestagingtherapy assessment |
| spellingShingle | Davide Donner Paola Feraco Linda Meneghello Barbara Rombi Lorena Picori Franca Chierichetti Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric Rhabdomyosarcoma Diagnostics <sup>18</sup>F-FDG PET-CT rhabdomyosarcoma pediatric staging restaging therapy assessment |
| title | Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric Rhabdomyosarcoma |
| title_full | Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric Rhabdomyosarcoma |
| title_fullStr | Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric Rhabdomyosarcoma |
| title_full_unstemmed | Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric Rhabdomyosarcoma |
| title_short | Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric Rhabdomyosarcoma |
| title_sort | usefulness of 18f fdg pet ct in staging restaging and response assessment in pediatric rhabdomyosarcoma |
| topic | <sup>18</sup>F-FDG PET-CT rhabdomyosarcoma pediatric staging restaging therapy assessment |
| url | https://www.mdpi.com/2075-4418/10/12/1112 |
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