MD11-mediated delivery of recombinant eIF3f induces melanoma and colorectal carcinoma cell death

MD11-mediated delivery of recombinant eIF3f induces melanoma and colorectal carcinoma cell death

The f subunit of the eukaryotic initiation factor 3 (eIF3f) is downregulated in several cancers and in particular in melanoma and pancreatic cancer cells. Its enforced expression by transient gene transfection negatively regulates cancer cell growth by activating apoptosis. With the aim to increase...

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Bibliographic Details
Main Authors:	Roberta Marchione, David Laurin, Lavinia Liguori, Marie P Leibovitch, Serge A Leibovitch, Jean-Luc Lenormand
Format:	Article
Language:	English
Published:	Elsevier 2015-01-01
Series:	Molecular Therapy: Methods & Clinical Development
Online Access:	http://www.sciencedirect.com/science/article/pii/S2329050116300018

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