Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-04-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340918300532 |
| _version_ | 1818269814801563648 |
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| author | Mehmet Ilyas Cosacak Ipek Erdogan Ayten Nalbant Bunyamin Akgul |
| author_facet | Mehmet Ilyas Cosacak Ipek Erdogan Ayten Nalbant Bunyamin Akgul |
| author_sort | Mehmet Ilyas Cosacak |
| collection | DOAJ |
| description | In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug and the other being relatively more resistant. We report new original data that include the frequency of tRNA-derived fragments (tRF) in drug-sensitive and resistant cells. We also present partially analyzed data to show the origin of reads on tRNAs as well as the borders of the fragments. We believe that this data can benefit the science community working in the field of tRF and/or apoptosis. |
| first_indexed | 2024-12-12T21:00:22Z |
| format | Article |
| id | doaj.art-4564d5207ccf4262987f8fe1b5e193e6 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-12T21:00:22Z |
| publishDate | 2018-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-4564d5207ccf4262987f8fe1b5e193e62022-12-22T00:12:10ZengElsevierData in Brief2352-34092018-04-0117397400Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecinMehmet Ilyas Cosacak0Ipek Erdogan1Ayten Nalbant2Bunyamin Akgul3Izmir Institute of Technology, Department of Molecular Biology and Genetics, Gulbahcekoyu, Urla, 35430 Izmir, Turkey; German Center for Neurodegenerative Diseases Dresden, DFG-Center for Regerenative Therapies Dresden, Cluster of Excellence, TU Dresden FetscherstraBe 105, 01307 Dresden, GermanyIzmir Institute of Technology, Department of Molecular Biology and Genetics, Gulbahcekoyu, Urla, 35430 Izmir, TurkeyIzmir Institute of Technology, Department of Molecular Biology and Genetics, Gulbahcekoyu, Urla, 35430 Izmir, TurkeyIzmir Institute of Technology, Department of Molecular Biology and Genetics, Gulbahcekoyu, Urla, 35430 Izmir, Turkey; Corresponding author.In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug and the other being relatively more resistant. We report new original data that include the frequency of tRNA-derived fragments (tRF) in drug-sensitive and resistant cells. We also present partially analyzed data to show the origin of reads on tRNAs as well as the borders of the fragments. We believe that this data can benefit the science community working in the field of tRF and/or apoptosis.http://www.sciencedirect.com/science/article/pii/S2352340918300532 |
| spellingShingle | Mehmet Ilyas Cosacak Ipek Erdogan Ayten Nalbant Bunyamin Akgul Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin Data in Brief |
| title | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
| title_full | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
| title_fullStr | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
| title_full_unstemmed | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
| title_short | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
| title_sort | small rna data set that includes trna derived fragments from jurkat cells treated with camptothecin |
| url | http://www.sciencedirect.com/science/article/pii/S2352340918300532 |
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