In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration
It is well known that three-dimensional (3D) printing is an emerging technology used to produce customized implants and surface characteristics of implants, strongly deciding their osseointegration ability. In this study, Ti alloy microspheres were printed under selected rational printing parameters...
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MDPI AG
2019-03-01
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| Online Access: | http://www.mdpi.com/1996-1944/12/5/815 |
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| author | Lijun Shan Abdul Amir H. Kadhum M.S.H. Al-Furjan Wenjian Weng Youping Gong Kui Cheng Maoying Zhou Lingqing Dong Guojin Chen Mohd S. Takriff Abu Bakar Sulong |
| author_facet | Lijun Shan Abdul Amir H. Kadhum M.S.H. Al-Furjan Wenjian Weng Youping Gong Kui Cheng Maoying Zhou Lingqing Dong Guojin Chen Mohd S. Takriff Abu Bakar Sulong |
| author_sort | Lijun Shan |
| collection | DOAJ |
| description | It is well known that three-dimensional (3D) printing is an emerging technology used to produce customized implants and surface characteristics of implants, strongly deciding their osseointegration ability. In this study, Ti alloy microspheres were printed under selected rational printing parameters in order to tailor the surface micro-characteristics of the printed implants during additive manufacturing by an in situ, controlled way. The laser path and hatching space were responsible for the appearance of the stripy structure (S), while the bulbous structure (B) and bulbous–stripy composite surface (BS) were determined by contour scanning. A nano-sized structure could be superposed by hydrothermal treatment. The cytocompatibility was evaluated by culturing Mouse calvaria-derived preosteoblastic cells (MC3T3-E1). The results showed that three typical microstructured surfaces, S, B, and BS, could be achieved by varying the 3D printing parameters. Moreover, the osteogenic differentiation potential of the S, B, and BS surfaces could be significantly enhanced, and the addition of nano-sized structures could be further improved. The BS surface with nano-sized structure demonstrated the optimum osteogenic differentiation potential. The present research demonstrated an in situ, controlled way to tailor and optimize the surface structures in micro-size during the 3D printing process for an implant with higher osseointegration ability. |
| first_indexed | 2024-04-12T07:19:15Z |
| format | Article |
| id | doaj.art-4567c1a9bc784283a5246675aa2caaa4 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-04-12T07:19:15Z |
| publishDate | 2019-03-01 |
| publisher | MDPI AG |
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| series | Materials |
| spelling | doaj.art-4567c1a9bc784283a5246675aa2caaa42022-12-22T03:42:22ZengMDPI AGMaterials1996-19442019-03-0112581510.3390/ma12050815ma12050815In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its OsteointegrationLijun Shan0Abdul Amir H. Kadhum1M.S.H. Al-Furjan2Wenjian Weng3Youping Gong4Kui Cheng5Maoying Zhou6Lingqing Dong7Guojin Chen8Mohd S. Takriff9Abu Bakar Sulong10Department of Chemical & Process Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor 43600, MalaysiaDepartment of Chemical & Process Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor 43600, MalaysiaSchool of Mechanical Engineering, Hangzhou Dianzi University, Hangzhou 310018, ChinaSchool of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University, Hangzhou 310018, ChinaSchool of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University, Hangzhou 310018, ChinaSchool of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University, Hangzhou 310018, ChinaResearch Center for Sustainable Process Technology (CESPRO), Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor 43600, MalaysiaDepartment of Mechanical and Materials Engineering, Universiti Kebangsaan Malaysia, Selangor 43600, MalaysiaIt is well known that three-dimensional (3D) printing is an emerging technology used to produce customized implants and surface characteristics of implants, strongly deciding their osseointegration ability. In this study, Ti alloy microspheres were printed under selected rational printing parameters in order to tailor the surface micro-characteristics of the printed implants during additive manufacturing by an in situ, controlled way. The laser path and hatching space were responsible for the appearance of the stripy structure (S), while the bulbous structure (B) and bulbous–stripy composite surface (BS) were determined by contour scanning. A nano-sized structure could be superposed by hydrothermal treatment. The cytocompatibility was evaluated by culturing Mouse calvaria-derived preosteoblastic cells (MC3T3-E1). The results showed that three typical microstructured surfaces, S, B, and BS, could be achieved by varying the 3D printing parameters. Moreover, the osteogenic differentiation potential of the S, B, and BS surfaces could be significantly enhanced, and the addition of nano-sized structures could be further improved. The BS surface with nano-sized structure demonstrated the optimum osteogenic differentiation potential. The present research demonstrated an in situ, controlled way to tailor and optimize the surface structures in micro-size during the 3D printing process for an implant with higher osseointegration ability.http://www.mdpi.com/1996-1944/12/5/8153D printingTi implantsosteogenesismicro-nano structured surfacein situ control |
| spellingShingle | Lijun Shan Abdul Amir H. Kadhum M.S.H. Al-Furjan Wenjian Weng Youping Gong Kui Cheng Maoying Zhou Lingqing Dong Guojin Chen Mohd S. Takriff Abu Bakar Sulong In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration Materials 3D printing Ti implants osteogenesis micro-nano structured surface in situ control |
| title | In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration |
| title_full | In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration |
| title_fullStr | In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration |
| title_full_unstemmed | In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration |
| title_short | In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration |
| title_sort | in situ controlled surface microstructure of 3d printed ti alloy to promote its osteointegration |
| topic | 3D printing Ti implants osteogenesis micro-nano structured surface in situ control |
| url | http://www.mdpi.com/1996-1944/12/5/815 |
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