Detection of Osmotic Shock-Induced Extracellular Nucleotide Release with a Genetically Encoded Fluorescent Sensor of ADP and ATP

Detection of Osmotic Shock-Induced Extracellular Nucleotide Release with a Genetically Encoded Fluorescent Sensor of ADP and ATP

Purinergic signals, such as extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP), mediate intercellular communication and stress responses throughout mammalian tissues, but the dynamics of their release and clearance are still not well understood. Although physiochemical method...

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Bibliographic Details
Main Authors: Keelan J. Trull, Piper Miller, Kiet Tat, S. Ashley Varney, Jason M. Conley, Mathew Tantama
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Sensors
Subjects:
extracellular ADP
purinergic signaling
fluorescent sensor
FRET
genetically encoded
Online Access:https://www.mdpi.com/1424-8220/19/15/3253

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