The longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners
BackgroundIt is currently unknown whether the dynamic nature of depression affects the development of sarcopenia. Herein, this study aims to assess the association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners through a 4-year longitudinal c...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.1001241/full |
| _version_ | 1811314526418632704 |
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| author | Yufeng Tian Yufeng Tian Zhigang Hu Zhigang Hu Zhigang Hu Xinyu Song Ailan Yang |
| author_facet | Yufeng Tian Yufeng Tian Zhigang Hu Zhigang Hu Zhigang Hu Xinyu Song Ailan Yang |
| author_sort | Yufeng Tian |
| collection | DOAJ |
| description | BackgroundIt is currently unknown whether the dynamic nature of depression affects the development of sarcopenia. Herein, this study aims to assess the association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners through a 4-year longitudinal cohort study.MethodsOur study included 784 pairs of individuals without possible sarcopenia and their spouses from the China Health and Retirement Longitudinal Study (CHARLS) 2011. All individuals and their spouses received three assessments of the Center for Epidemiologic Studies Depression 10-item (CESD-10) scale in 2011, 2013, and 2015. According to the diagnostic algorithm recommended by the Asian Working Group for Sarcopenia (AWGS) 2019, we evaluated the incidence of possible sarcopenia in individuals in 2015. Latent class analysis (LCA) was used to identify a longitudinal depression trajectory of individuals and their spouses during a 4-year follow-up. Subsequently, we assessed the relationship between possible sarcopenia and depression trajectory using three generalized additive models.ResultsIn 2015, 24.87% (195/784) of individuals were diagnosed with possible sarcopenia. LCA identified five depression trajectories: a persistently high risk of depression in individuals and their spouses (reference; class 1 = 34 [4.3%]); a persistently low risk of depression in individuals and their spouses (class 2 = 526 [67.1%]); a high risk of depression in individuals and a low risk of depression in spouses (class 3 = 46 [5.9%]); a low risk of depression in individuals and a high risk of depression in spouses (class 4 = 116 [14.8%]); and a reduced risk of depression in individuals and their spouses (class 5 = 62 [7.9%]). The highest incidence of possible sarcopenia was shown in class 1, followed by classes 3 and 5. Classes 2 (adjusted relative risk (RR) = 0.44, 95% confidence interval (CI): 0.20–0.97) and 4 (adjusted RR = 0.40, 95%CI: 0.17–0.96) had a significantly lower incidence of possible sarcopenia than class 1. Subgroup analysis demonstrated that the incidence of possible sarcopenia in class 4 was obviously higher in women (38.89%) than in men (18.4%).ConclusionsOur study indicates a persistently high risk of depression in individuals to develop possible sarcopenia. In addition, a persistently high risk of depression in intimate partners potentially increases the risk of possible new sarcopenia, especially in female individuals who are at low risk of depression. |
| first_indexed | 2024-04-13T11:13:11Z |
| format | Article |
| id | doaj.art-4569aca9f9c94ac7a9cb2570db74097e |
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| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-13T11:13:11Z |
| publishDate | 2022-12-01 |
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| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-4569aca9f9c94ac7a9cb2570db74097e2022-12-22T02:49:03ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652022-12-011410.3389/fnagi.2022.10012411001241The longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partnersYufeng Tian0Yufeng Tian1Zhigang Hu2Zhigang Hu3Zhigang Hu4Xinyu Song5Ailan Yang6Department of Evidence Based Medicine Center, The First College of Clinical Medicine Science, China Three Gorges University, Yichang, ChinaDepartment of Academic Management, Clinical Research Center, China Three Gorges University, Yichang, ChinaDepartment of Evidence Based Medicine Center, The First College of Clinical Medicine Science, China Three Gorges University, Yichang, ChinaDepartment of Respiratory and Critical Care Medicine, Yichang Central People's Hospital at Zhijiang, Zhijiang, ChinaDepartment of Respiratory and Critical Care Medicine, Yichang Central People's Hospital, Yichang, ChinaDepartment of Respiratory and Critical Care Medicine, Yichang Central People's Hospital, Yichang, ChinaDepartment of Respiratory and Critical Care Medicine, Yichang Central People's Hospital at Zhijiang, Zhijiang, ChinaBackgroundIt is currently unknown whether the dynamic nature of depression affects the development of sarcopenia. Herein, this study aims to assess the association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners through a 4-year longitudinal cohort study.MethodsOur study included 784 pairs of individuals without possible sarcopenia and their spouses from the China Health and Retirement Longitudinal Study (CHARLS) 2011. All individuals and their spouses received three assessments of the Center for Epidemiologic Studies Depression 10-item (CESD-10) scale in 2011, 2013, and 2015. According to the diagnostic algorithm recommended by the Asian Working Group for Sarcopenia (AWGS) 2019, we evaluated the incidence of possible sarcopenia in individuals in 2015. Latent class analysis (LCA) was used to identify a longitudinal depression trajectory of individuals and their spouses during a 4-year follow-up. Subsequently, we assessed the relationship between possible sarcopenia and depression trajectory using three generalized additive models.ResultsIn 2015, 24.87% (195/784) of individuals were diagnosed with possible sarcopenia. LCA identified five depression trajectories: a persistently high risk of depression in individuals and their spouses (reference; class 1 = 34 [4.3%]); a persistently low risk of depression in individuals and their spouses (class 2 = 526 [67.1%]); a high risk of depression in individuals and a low risk of depression in spouses (class 3 = 46 [5.9%]); a low risk of depression in individuals and a high risk of depression in spouses (class 4 = 116 [14.8%]); and a reduced risk of depression in individuals and their spouses (class 5 = 62 [7.9%]). The highest incidence of possible sarcopenia was shown in class 1, followed by classes 3 and 5. Classes 2 (adjusted relative risk (RR) = 0.44, 95% confidence interval (CI): 0.20–0.97) and 4 (adjusted RR = 0.40, 95%CI: 0.17–0.96) had a significantly lower incidence of possible sarcopenia than class 1. Subgroup analysis demonstrated that the incidence of possible sarcopenia in class 4 was obviously higher in women (38.89%) than in men (18.4%).ConclusionsOur study indicates a persistently high risk of depression in individuals to develop possible sarcopenia. In addition, a persistently high risk of depression in intimate partners potentially increases the risk of possible new sarcopenia, especially in female individuals who are at low risk of depression.https://www.frontiersin.org/articles/10.3389/fnagi.2022.1001241/fulldepressionintimate partnerstrajectorysex differencepossible sarcopenia |
| spellingShingle | Yufeng Tian Yufeng Tian Zhigang Hu Zhigang Hu Zhigang Hu Xinyu Song Ailan Yang The longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners Frontiers in Aging Neuroscience depression intimate partners trajectory sex difference possible sarcopenia |
| title | The longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners |
| title_full | The longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners |
| title_fullStr | The longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners |
| title_full_unstemmed | The longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners |
| title_short | The longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners |
| title_sort | longitudinal association between possible new sarcopenia and the depression trajectory of individuals and their intimate partners |
| topic | depression intimate partners trajectory sex difference possible sarcopenia |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2022.1001241/full |
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