Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review

Cyperaceae is a cosmopolitan plant family with approx. 5000 species distributed worldwide. Several members of this family are used in traditional medicines for the treatment of different diseases. In the last few decades, constituents with great chemical diversity were isolated from sedges, and a wi...

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Main Authors: Csilla Zsuzsanna Dávid, Judit Hohmann, Andrea Vasas
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/9/2794
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author Csilla Zsuzsanna Dávid
Judit Hohmann
Andrea Vasas
author_facet Csilla Zsuzsanna Dávid
Judit Hohmann
Andrea Vasas
author_sort Csilla Zsuzsanna Dávid
collection DOAJ
description Cyperaceae is a cosmopolitan plant family with approx. 5000 species distributed worldwide. Several members of this family are used in traditional medicines for the treatment of different diseases. In the last few decades, constituents with great chemical diversity were isolated from sedges, and a wide range of biological activities were detected either for crude extracts or for pure compounds. Among the isolated compounds, phenolic derivatives are the most important, especially stilbenoids, and flavonoids. To date, more than 60 stilbenoids were isolated from 28 Cyperaceae species. Pharmacological investigation of Cyperaceae stilbenoids revealed that several compounds possess promising activities; mainly antiproliferative, antibacterial, antioxidant and anthelmintic effects. Isolation, synthesis and pharmacological investigation of stilbenes are increasing constantly. As Cyperaceae species are very good sources of a wide variety of stilbenes, and several of them occur in large amount worldwide, they are worthy for phytochemical and pharmacological investigations. Moreover, stilbenes are important from chemotaxonomical point of view, and they play a key role in plant defense mechanisms as well. This review summarizes the stilbenoids isolated from sedges, and their biological activities.
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spelling doaj.art-456d45bd3da84711be6beca22035f4ea2023-11-21T18:56:05ZengMDPI AGMolecules1420-30492021-05-01269279410.3390/molecules26092794Chemistry and Pharmacology of Cyperaceae Stilbenoids: A ReviewCsilla Zsuzsanna Dávid0Judit Hohmann1Andrea Vasas2Department of Pharmacognosy, Interdisciplinary Excellence Centre, University of Szeged, Eötvös u. 6, 6720 Szeged, HungaryDepartment of Pharmacognosy, Interdisciplinary Excellence Centre, University of Szeged, Eötvös u. 6, 6720 Szeged, HungaryDepartment of Pharmacognosy, Interdisciplinary Excellence Centre, University of Szeged, Eötvös u. 6, 6720 Szeged, HungaryCyperaceae is a cosmopolitan plant family with approx. 5000 species distributed worldwide. Several members of this family are used in traditional medicines for the treatment of different diseases. In the last few decades, constituents with great chemical diversity were isolated from sedges, and a wide range of biological activities were detected either for crude extracts or for pure compounds. Among the isolated compounds, phenolic derivatives are the most important, especially stilbenoids, and flavonoids. To date, more than 60 stilbenoids were isolated from 28 Cyperaceae species. Pharmacological investigation of Cyperaceae stilbenoids revealed that several compounds possess promising activities; mainly antiproliferative, antibacterial, antioxidant and anthelmintic effects. Isolation, synthesis and pharmacological investigation of stilbenes are increasing constantly. As Cyperaceae species are very good sources of a wide variety of stilbenes, and several of them occur in large amount worldwide, they are worthy for phytochemical and pharmacological investigations. Moreover, stilbenes are important from chemotaxonomical point of view, and they play a key role in plant defense mechanisms as well. This review summarizes the stilbenoids isolated from sedges, and their biological activities.https://www.mdpi.com/1420-3049/26/9/2794<i>Carex</i><i>Cyperus</i><i>Scirpus</i>resveratrolstilbenoid dimersoligostilbenoids
spellingShingle Csilla Zsuzsanna Dávid
Judit Hohmann
Andrea Vasas
Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review
Molecules
<i>Carex</i>
<i>Cyperus</i>
<i>Scirpus</i>
resveratrol
stilbenoid dimers
oligostilbenoids
title Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review
title_full Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review
title_fullStr Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review
title_full_unstemmed Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review
title_short Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review
title_sort chemistry and pharmacology of cyperaceae stilbenoids a review
topic <i>Carex</i>
<i>Cyperus</i>
<i>Scirpus</i>
resveratrol
stilbenoid dimers
oligostilbenoids
url https://www.mdpi.com/1420-3049/26/9/2794
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