Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report)
<p>Abstract</p> <p>A case of leptomeningeal carcinomatosis in a patient with known brain and lung metastases from renal cell cancer without previous systemic therapy is presented. Neoplastic meningitis (NM) developed 31 months after first diagnosis of simultaneous extra- and intrac...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-05-01
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| Series: | World Journal of Surgical Oncology |
| Online Access: | http://www.wjso.com/content/8/1/36 |
| _version_ | 1828795427698245632 |
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| author | Haukland Ellinor Dalhaug Astrid Nieder Carsten |
| author_facet | Haukland Ellinor Dalhaug Astrid Nieder Carsten |
| author_sort | Haukland Ellinor |
| collection | DOAJ |
| description | <p>Abstract</p> <p>A case of leptomeningeal carcinomatosis in a patient with known brain and lung metastases from renal cell cancer without previous systemic therapy is presented. Neoplastic meningitis (NM) developed 31 months after first diagnosis of simultaneous extra- and intracranial recurrence of kidney cancer and surgical resection of a cerebellar metastasis. In spite of local radiotherapy to the macroscopic NM lesions in the cervical and lumbar spine followed by initiation of sunitinib, the patient succumbed to his disease 4 months after the diagnosis of NM. The untreated lung metastases progressed very slowly during almost 3 years of observation. This case illustrates important issues around both biological behaviour and treatment approaches in metastatic renal cell cancer.</p> |
| first_indexed | 2024-12-12T04:03:44Z |
| format | Article |
| id | doaj.art-457180b1215540a1a67d79637887d6c1 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-12T04:03:44Z |
| publishDate | 2010-05-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-457180b1215540a1a67d79637887d6c12022-12-22T00:38:49ZengBMCWorld Journal of Surgical Oncology1477-78192010-05-01813610.1186/1477-7819-8-36Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report)Haukland EllinorDalhaug AstridNieder Carsten<p>Abstract</p> <p>A case of leptomeningeal carcinomatosis in a patient with known brain and lung metastases from renal cell cancer without previous systemic therapy is presented. Neoplastic meningitis (NM) developed 31 months after first diagnosis of simultaneous extra- and intracranial recurrence of kidney cancer and surgical resection of a cerebellar metastasis. In spite of local radiotherapy to the macroscopic NM lesions in the cervical and lumbar spine followed by initiation of sunitinib, the patient succumbed to his disease 4 months after the diagnosis of NM. The untreated lung metastases progressed very slowly during almost 3 years of observation. This case illustrates important issues around both biological behaviour and treatment approaches in metastatic renal cell cancer.</p>http://www.wjso.com/content/8/1/36 |
| spellingShingle | Haukland Ellinor Dalhaug Astrid Nieder Carsten Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report) World Journal of Surgical Oncology |
| title | Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report) |
| title_full | Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report) |
| title_fullStr | Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report) |
| title_full_unstemmed | Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report) |
| title_short | Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report) |
| title_sort | leptomeningeal carcinomatosis from renal cell cancer treatment attempt with radiation and sunitinib case report |
| url | http://www.wjso.com/content/8/1/36 |
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