Low Intensity Respiratory Muscle Training in COVID-19 Patients after Invasive Mechanical Ventilation: A Retrospective Case-Series Study
Worldwide, healthcare systems had to respond to an exponential increase in COVID-19 patients with a noteworthy increment in intensive care units (ICU) admissions and invasive mechanical ventilation (IMV). The aim was to determine low intensity respiratory muscle training (RMT) effects in COVID-19 pa...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/11/2807 |
| _version_ | 1797468984613797888 |
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| author | Koldo Villelabeitia-Jaureguizar César Calvo-Lobo David Rodríguez-Sanz Davinia Vicente-Campos José Adrián Castro-Portal Marta López-Cañadas Ricardo Becerro-de-Bengoa-Vallejo José López Chicharro |
| author_facet | Koldo Villelabeitia-Jaureguizar César Calvo-Lobo David Rodríguez-Sanz Davinia Vicente-Campos José Adrián Castro-Portal Marta López-Cañadas Ricardo Becerro-de-Bengoa-Vallejo José López Chicharro |
| author_sort | Koldo Villelabeitia-Jaureguizar |
| collection | DOAJ |
| description | Worldwide, healthcare systems had to respond to an exponential increase in COVID-19 patients with a noteworthy increment in intensive care units (ICU) admissions and invasive mechanical ventilation (IMV). The aim was to determine low intensity respiratory muscle training (RMT) effects in COVID-19 patients upon medical discharge and after an ICU stay with IMV. A retrospective case-series study was performed. Forty COVID-19 patients were enrolled and divided into twenty participants who received IMV during ICU stay (IMV group) and 20 participants who did not receive IMV nor an ICU stay (non-IMV group). Maximal expiratory pressure (PE<sub>max</sub>), maximal inspiratory pressure (PI<sub>max</sub>), COPD assessment test (CAT) and Medical Research Council (MRC) dyspnea scale were collected at baseline and after 12 weeks of low intensity RMT. A greater MRC dyspnea score and lower PI<sub>max</sub> were shown at baseline in the IMV group versus the non-IMV group (<i>p</i> < 0.01). RMT effects on the total sample improved all outcome measurements (<i>p</i> < 0.05; <i>d</i> = 0.38–0.98). Intragroup comparisons after RMT improved PI<sub>max</sub>, CAT and MRC scores in the IMV group (<i>p</i> = 0.001; <i>d</i> = 0.94–1.09), but not for PI<sub>max</sub> in the non-IMV group (<i>p</i> > 0.05). Between-groups comparison after RMT only showed MRC dyspnea improvements (<i>p</i> = 0.020; <i>d</i> = 0.74) in the IMV group versus non-IMV group. Furthermore, PI<sub>max</sub> decrease was only predicted by the IMV presence (<i>R</i><sup>2</sup> = 0.378). Low intensity RMT may improve respiratory muscle strength, health related quality of life and dyspnea in COVID-19 patients. Especially, low intensity RMT could improve dyspnea level and maybe PI<sub>max</sub> in COVID-19 patients who received IMV in ICU. |
| first_indexed | 2024-03-09T19:15:02Z |
| format | Article |
| id | doaj.art-4572c6f0fbe74de3b7dc6068dcc272c3 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T19:15:02Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-4572c6f0fbe74de3b7dc6068dcc272c32023-11-24T03:51:01ZengMDPI AGBiomedicines2227-90592022-11-011011280710.3390/biomedicines10112807Low Intensity Respiratory Muscle Training in COVID-19 Patients after Invasive Mechanical Ventilation: A Retrospective Case-Series StudyKoldo Villelabeitia-Jaureguizar0César Calvo-Lobo1David Rodríguez-Sanz2Davinia Vicente-Campos3José Adrián Castro-Portal4Marta López-Cañadas5Ricardo Becerro-de-Bengoa-Vallejo6José López Chicharro7Infanta Elena University Hospital, Valdemoro, 28342 Madrid, SpainFaculty of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid, 28040 Madrid, SpainFaculty of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid, 28040 Madrid, SpainFaculty of Health Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, SpainInfanta Elena University Hospital, Valdemoro, 28342 Madrid, SpainInfanta Elena University Hospital, Valdemoro, 28342 Madrid, SpainFaculty of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid, 28040 Madrid, SpainFaculty of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid, 28040 Madrid, SpainWorldwide, healthcare systems had to respond to an exponential increase in COVID-19 patients with a noteworthy increment in intensive care units (ICU) admissions and invasive mechanical ventilation (IMV). The aim was to determine low intensity respiratory muscle training (RMT) effects in COVID-19 patients upon medical discharge and after an ICU stay with IMV. A retrospective case-series study was performed. Forty COVID-19 patients were enrolled and divided into twenty participants who received IMV during ICU stay (IMV group) and 20 participants who did not receive IMV nor an ICU stay (non-IMV group). Maximal expiratory pressure (PE<sub>max</sub>), maximal inspiratory pressure (PI<sub>max</sub>), COPD assessment test (CAT) and Medical Research Council (MRC) dyspnea scale were collected at baseline and after 12 weeks of low intensity RMT. A greater MRC dyspnea score and lower PI<sub>max</sub> were shown at baseline in the IMV group versus the non-IMV group (<i>p</i> < 0.01). RMT effects on the total sample improved all outcome measurements (<i>p</i> < 0.05; <i>d</i> = 0.38–0.98). Intragroup comparisons after RMT improved PI<sub>max</sub>, CAT and MRC scores in the IMV group (<i>p</i> = 0.001; <i>d</i> = 0.94–1.09), but not for PI<sub>max</sub> in the non-IMV group (<i>p</i> > 0.05). Between-groups comparison after RMT only showed MRC dyspnea improvements (<i>p</i> = 0.020; <i>d</i> = 0.74) in the IMV group versus non-IMV group. Furthermore, PI<sub>max</sub> decrease was only predicted by the IMV presence (<i>R</i><sup>2</sup> = 0.378). Low intensity RMT may improve respiratory muscle strength, health related quality of life and dyspnea in COVID-19 patients. Especially, low intensity RMT could improve dyspnea level and maybe PI<sub>max</sub> in COVID-19 patients who received IMV in ICU.https://www.mdpi.com/2227-9059/10/11/2807COVID-19respiratory muscle traininginvasive mechanical ventilationdyspnea |
| spellingShingle | Koldo Villelabeitia-Jaureguizar César Calvo-Lobo David Rodríguez-Sanz Davinia Vicente-Campos José Adrián Castro-Portal Marta López-Cañadas Ricardo Becerro-de-Bengoa-Vallejo José López Chicharro Low Intensity Respiratory Muscle Training in COVID-19 Patients after Invasive Mechanical Ventilation: A Retrospective Case-Series Study Biomedicines COVID-19 respiratory muscle training invasive mechanical ventilation dyspnea |
| title | Low Intensity Respiratory Muscle Training in COVID-19 Patients after Invasive Mechanical Ventilation: A Retrospective Case-Series Study |
| title_full | Low Intensity Respiratory Muscle Training in COVID-19 Patients after Invasive Mechanical Ventilation: A Retrospective Case-Series Study |
| title_fullStr | Low Intensity Respiratory Muscle Training in COVID-19 Patients after Invasive Mechanical Ventilation: A Retrospective Case-Series Study |
| title_full_unstemmed | Low Intensity Respiratory Muscle Training in COVID-19 Patients after Invasive Mechanical Ventilation: A Retrospective Case-Series Study |
| title_short | Low Intensity Respiratory Muscle Training in COVID-19 Patients after Invasive Mechanical Ventilation: A Retrospective Case-Series Study |
| title_sort | low intensity respiratory muscle training in covid 19 patients after invasive mechanical ventilation a retrospective case series study |
| topic | COVID-19 respiratory muscle training invasive mechanical ventilation dyspnea |
| url | https://www.mdpi.com/2227-9059/10/11/2807 |
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