Endoscopic Submucosal Dissection for Gastric Epithelial Tumors: A Multicenter Study in Taiwan
Endoscopic submucosal dissection (ESD) is an advanced endoscopic procedure to resect early gastric cancer (EGC). The purpose of this study was to determine the effectiveness and complications of ESD for gastric epithelial tumors in Taiwan. Methods: We retrospectively analyzed the efficacy and outcom...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2009-01-01
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| Series: | Journal of the Formosan Medical Association |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664609600309 |
| _version_ | 1818855701946040320 |
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| author | Chun-Chao Chang I-Lin Lee Peng-Jen Chen Hsiu-Po Wang Ming-Chih Hou Ching-Tai Lee Yang-Yuan Chen Yeh-Pin Cho Jaw-Town Lin |
| author_facet | Chun-Chao Chang I-Lin Lee Peng-Jen Chen Hsiu-Po Wang Ming-Chih Hou Ching-Tai Lee Yang-Yuan Chen Yeh-Pin Cho Jaw-Town Lin |
| author_sort | Chun-Chao Chang |
| collection | DOAJ |
| description | Endoscopic submucosal dissection (ESD) is an advanced endoscopic procedure to resect early gastric cancer (EGC). The purpose of this study was to determine the effectiveness and complications of ESD for gastric epithelial tumors in Taiwan.
Methods: We retrospectively analyzed the efficacy and outcome of ESD in patients who received ESD for gastric epithelial tumors between June 2004 and August 2007.
Results: A total of 70 patients with gastric epithelial tumors were treated by ESD. The mean age was 66.5 ±12.9 years (range, 35–84 years). The mean size of the gastric epithelial tumors was 1.85 ± 0.81 cm. The mean size of resected specimens was 3.26 ± 1.39 cm. The one-piece resection rate was 91.4% (64/70). The median operation time was 92.4 minutes. The complicating bleeding and perforation rates were 5.7% (4/70) and 4.3% (3/70), respectively. Emergency surgery was performed for three patients with perforations. The local recurrence rate of gastric cancer was 2.8%. Except for one patient who died of congestive heart failure and another who died of stroke, the remaining 68 patients (97.1%) survived.
Conclusion: ESD is a promising local curative treatment option for EGC in Taiwan but it still carries risks of perforation and bleeding. The education and learning curve of endoscopists will improve the outcome of this procedure. |
| first_indexed | 2024-12-19T08:12:48Z |
| format | Article |
| id | doaj.art-457581a889474b0f8c7e9a9719826a4c |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-19T08:12:48Z |
| publishDate | 2009-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-457581a889474b0f8c7e9a9719826a4c2022-12-21T20:29:34ZengElsevierJournal of the Formosan Medical Association0929-66462009-01-011081384410.1016/S0929-6646(09)60030-9Endoscopic Submucosal Dissection for Gastric Epithelial Tumors: A Multicenter Study in TaiwanChun-Chao Chang0I-Lin Lee1Peng-Jen Chen2Hsiu-Po Wang3Ming-Chih Hou4Ching-Tai Lee5Yang-Yuan Chen6Yeh-Pin Cho7Jaw-Town Lin8Division of Gastroenterology, Taipei Medical University Hospital, TaipeiDivision of Gastroenterology, Chiayi Chang Gung Memorial Hospital, ChiayiDivision of Gastroenterology, Tri-Service General Hospital, TaipeiDivision of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital, TaipeiDivision of Gastroenterology, Taipei Veterans General Hospital, TaipeiDivision of Gastroenterology, E-Da Hospital, KaohsiungDivision of Gastroenterology, Changhua Christian Hospital, ChanghuaDivision of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanDivision of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital, TaipeiEndoscopic submucosal dissection (ESD) is an advanced endoscopic procedure to resect early gastric cancer (EGC). The purpose of this study was to determine the effectiveness and complications of ESD for gastric epithelial tumors in Taiwan. Methods: We retrospectively analyzed the efficacy and outcome of ESD in patients who received ESD for gastric epithelial tumors between June 2004 and August 2007. Results: A total of 70 patients with gastric epithelial tumors were treated by ESD. The mean age was 66.5 ±12.9 years (range, 35–84 years). The mean size of the gastric epithelial tumors was 1.85 ± 0.81 cm. The mean size of resected specimens was 3.26 ± 1.39 cm. The one-piece resection rate was 91.4% (64/70). The median operation time was 92.4 minutes. The complicating bleeding and perforation rates were 5.7% (4/70) and 4.3% (3/70), respectively. Emergency surgery was performed for three patients with perforations. The local recurrence rate of gastric cancer was 2.8%. Except for one patient who died of congestive heart failure and another who died of stroke, the remaining 68 patients (97.1%) survived. Conclusion: ESD is a promising local curative treatment option for EGC in Taiwan but it still carries risks of perforation and bleeding. The education and learning curve of endoscopists will improve the outcome of this procedure.http://www.sciencedirect.com/science/article/pii/S0929664609600309endoscopic submucosal dissectiongastric epithelial tumors |
| spellingShingle | Chun-Chao Chang I-Lin Lee Peng-Jen Chen Hsiu-Po Wang Ming-Chih Hou Ching-Tai Lee Yang-Yuan Chen Yeh-Pin Cho Jaw-Town Lin Endoscopic Submucosal Dissection for Gastric Epithelial Tumors: A Multicenter Study in Taiwan Journal of the Formosan Medical Association endoscopic submucosal dissection gastric epithelial tumors |
| title | Endoscopic Submucosal Dissection for Gastric Epithelial Tumors: A Multicenter Study in Taiwan |
| title_full | Endoscopic Submucosal Dissection for Gastric Epithelial Tumors: A Multicenter Study in Taiwan |
| title_fullStr | Endoscopic Submucosal Dissection for Gastric Epithelial Tumors: A Multicenter Study in Taiwan |
| title_full_unstemmed | Endoscopic Submucosal Dissection for Gastric Epithelial Tumors: A Multicenter Study in Taiwan |
| title_short | Endoscopic Submucosal Dissection for Gastric Epithelial Tumors: A Multicenter Study in Taiwan |
| title_sort | endoscopic submucosal dissection for gastric epithelial tumors a multicenter study in taiwan |
| topic | endoscopic submucosal dissection gastric epithelial tumors |
| url | http://www.sciencedirect.com/science/article/pii/S0929664609600309 |
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