Synthesis, Characterization and Biological Evaluation of New Dithiocarbamate Ligand and Its Complexes with some Metal Ions
New bidentate dithiocarbamate ligand (NaL) namely [Sodium-2-(((3-methyl -4- “(2,2,2-tri fluoro ethoxy) pyridin-2â€-yl) methyl) sulfinyl)-1H-benzoimidazole -1-carbodithioate] was prepared. This free ligand was synthesized from the reaction of a (RS)-2-([3-methyl -4-(2,2,2-tri fluoroethoxy) pyrid...
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| Format: | Article |
| Language: | English |
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University of Baghdad
2017-12-01
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| Series: | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| Subjects: | |
| Online Access: | https://jih.uobaghdad.edu.iq/index.php/j/article/view/1617 |
| _version_ | 1817982369617936384 |
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| author | Ahmed T. Numan Kaiss R. Ibraheem Mohammed K. Ibrahim |
| author_facet | Ahmed T. Numan Kaiss R. Ibraheem Mohammed K. Ibrahim |
| author_sort | Ahmed T. Numan |
| collection | DOAJ |
| description |
New bidentate dithiocarbamate ligand (NaL) namely [Sodium-2-(((3-methyl -4- “(2,2,2-tri fluoro ethoxy) pyridin-2â€-yl) methyl) sulfinyl)-1H-benzoimidazole -1-carbodithioate] was prepared. This free ligand was synthesized from the reaction of a (RS)-2-([3-methyl -4-(2,2,2-tri fluoroethoxy) pyridin-2-yl] methyl sulfinyl)-1H benzoimidazole, CS2 and NaOH in methanol as solvent. From reaction of dithiocarbamate salt (NaL) with metal ions (M); Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Pd(II)â€, have obtained the DTC complexes at general molecular formula [M(L)2(H2O)2] and [Pd(L)2]. To characterize the ligand and its complexes, used different analyses methods such FTIR, UV-Vis, elemental microanalysis, atomic absoreption, magnetic susceptibility, conductance, melting points, 1H- 13C- NMR spectroscopy, thermal analysis and mass spectrum. These studies indicated the formation of DTC complexes which their geometries about metal centers are octahedral; except Pd-complex is square planer. The bacterial activity evaluation against investigated bacterial species indicated that the metal complexes are more active than the free ligand when compared them.
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| first_indexed | 2024-04-13T23:20:34Z |
| format | Article |
| id | doaj.art-4575be86284e4b8e84102773a0807108 |
| institution | Directory Open Access Journal |
| issn | 1609-4042 2521-3407 |
| language | English |
| last_indexed | 2024-04-13T23:20:34Z |
| publishDate | 2017-12-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| spelling | doaj.art-4575be86284e4b8e84102773a08071082022-12-22T02:25:16ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072017-12-0130310.30526/30.3.1617Synthesis, Characterization and Biological Evaluation of New Dithiocarbamate Ligand and Its Complexes with some Metal IonsAhmed T. NumanKaiss R. IbraheemMohammed K. Ibrahim New bidentate dithiocarbamate ligand (NaL) namely [Sodium-2-(((3-methyl -4- “(2,2,2-tri fluoro ethoxy) pyridin-2â€-yl) methyl) sulfinyl)-1H-benzoimidazole -1-carbodithioate] was prepared. This free ligand was synthesized from the reaction of a (RS)-2-([3-methyl -4-(2,2,2-tri fluoroethoxy) pyridin-2-yl] methyl sulfinyl)-1H benzoimidazole, CS2 and NaOH in methanol as solvent. From reaction of dithiocarbamate salt (NaL) with metal ions (M); Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Pd(II)â€, have obtained the DTC complexes at general molecular formula [M(L)2(H2O)2] and [Pd(L)2]. To characterize the ligand and its complexes, used different analyses methods such FTIR, UV-Vis, elemental microanalysis, atomic absoreption, magnetic susceptibility, conductance, melting points, 1H- 13C- NMR spectroscopy, thermal analysis and mass spectrum. These studies indicated the formation of DTC complexes which their geometries about metal centers are octahedral; except Pd-complex is square planer. The bacterial activity evaluation against investigated bacterial species indicated that the metal complexes are more active than the free ligand when compared them. https://jih.uobaghdad.edu.iq/index.php/j/article/view/1617Dithiocarbamate complexes; metal ions; Characterization; Bacterial activity |
| spellingShingle | Ahmed T. Numan Kaiss R. Ibraheem Mohammed K. Ibrahim Synthesis, Characterization and Biological Evaluation of New Dithiocarbamate Ligand and Its Complexes with some Metal Ions Ibn Al-Haitham Journal for Pure and Applied Sciences Dithiocarbamate complexes; metal ions; Characterization; Bacterial activity |
| title | Synthesis, Characterization and Biological Evaluation of New Dithiocarbamate Ligand and Its Complexes with some Metal Ions |
| title_full | Synthesis, Characterization and Biological Evaluation of New Dithiocarbamate Ligand and Its Complexes with some Metal Ions |
| title_fullStr | Synthesis, Characterization and Biological Evaluation of New Dithiocarbamate Ligand and Its Complexes with some Metal Ions |
| title_full_unstemmed | Synthesis, Characterization and Biological Evaluation of New Dithiocarbamate Ligand and Its Complexes with some Metal Ions |
| title_short | Synthesis, Characterization and Biological Evaluation of New Dithiocarbamate Ligand and Its Complexes with some Metal Ions |
| title_sort | synthesis characterization and biological evaluation of new dithiocarbamate ligand and its complexes with some metal ions |
| topic | Dithiocarbamate complexes; metal ions; Characterization; Bacterial activity |
| url | https://jih.uobaghdad.edu.iq/index.php/j/article/view/1617 |
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