Adipokines and Inflammation: Focus on Cardiovascular Diseases
It is well established that adipose tissue, apart from its energy storage function, acts as an endocrine organ that produces and secretes a number of bioactive substances, including hormones commonly known as adipokines. Obesity is a major risk factor for the development of cardiovascular diseases,...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-10-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/21/20/7711 |
| _version_ | 1797550582230155264 |
|---|---|
| author | Sandra Feijóo-Bandín Alana Aragón-Herrera Sandra Moraña-Fernández Laura Anido-Varela Estefanía Tarazón Esther Roselló-Lletí Manuel Portolés Isabel Moscoso Oreste Gualillo José Ramón González-Juanatey Francisca Lago |
| author_facet | Sandra Feijóo-Bandín Alana Aragón-Herrera Sandra Moraña-Fernández Laura Anido-Varela Estefanía Tarazón Esther Roselló-Lletí Manuel Portolés Isabel Moscoso Oreste Gualillo José Ramón González-Juanatey Francisca Lago |
| author_sort | Sandra Feijóo-Bandín |
| collection | DOAJ |
| description | It is well established that adipose tissue, apart from its energy storage function, acts as an endocrine organ that produces and secretes a number of bioactive substances, including hormones commonly known as adipokines. Obesity is a major risk factor for the development of cardiovascular diseases, mainly due to a low grade of inflammation and the excessive fat accumulation produced in this state. The adipose tissue dysfunction in obesity leads to an aberrant release of adipokines, some of them with direct cardiovascular and inflammatory regulatory functions. Inflammation is a common link between obesity and cardiovascular diseases, so this review will summarise the role of the main adipokines implicated in the regulation of the inflammatory processes occurring under the scenario of cardiovascular diseases. |
| first_indexed | 2024-03-10T15:31:24Z |
| format | Article |
| id | doaj.art-45761cf89d5a45f0a37ff4256baaf4bd |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T15:31:24Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-45761cf89d5a45f0a37ff4256baaf4bd2023-11-20T17:35:31ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-10-012120771110.3390/ijms21207711Adipokines and Inflammation: Focus on Cardiovascular DiseasesSandra Feijóo-Bandín0Alana Aragón-Herrera1Sandra Moraña-Fernández2Laura Anido-Varela3Estefanía Tarazón4Esther Roselló-Lletí5Manuel Portolés6Isabel Moscoso7Oreste Gualillo8José Ramón González-Juanatey9Francisca Lago10Cellular and Molecular Cardiology Unit and Department of Cardiology, Institute of Biomedical Research of Santiago de Compostela (IDIS-SERGAS), Travesía Choupana s/n, 15706 Santiago de Compostela, SpainCellular and Molecular Cardiology Unit and Department of Cardiology, Institute of Biomedical Research of Santiago de Compostela (IDIS-SERGAS), Travesía Choupana s/n, 15706 Santiago de Compostela, SpainCellular and Molecular Cardiology Unit and Department of Cardiology, Institute of Biomedical Research of Santiago de Compostela (IDIS-SERGAS), Travesía Choupana s/n, 15706 Santiago de Compostela, SpainCellular and Molecular Cardiology Unit and Department of Cardiology, Institute of Biomedical Research of Santiago de Compostela (IDIS-SERGAS), Travesía Choupana s/n, 15706 Santiago de Compostela, SpainCIBERCV, Institute of Health Carlos III, C/Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, SpainCIBERCV, Institute of Health Carlos III, C/Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, SpainCIBERCV, Institute of Health Carlos III, C/Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, SpainCIBERCV, Institute of Health Carlos III, C/Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, SpainSERGAS (Servizo Galego de Saude): Área Sanitaria de Santiago de Compostela e Barbanza. Santiago University Clinical Hospital, Research Laboratory 9, 15706 Santiago de Compostela, Spain and IDIS (Instituto de Investigación Sanitaria de Santiago), The NEIRID Group (NeuroEndocrine Interactions in Rheumatic and Inflammatory Diseases) C027, 15706 Santiago de Compostela, SpainCellular and Molecular Cardiology Unit and Department of Cardiology, Institute of Biomedical Research of Santiago de Compostela (IDIS-SERGAS), Travesía Choupana s/n, 15706 Santiago de Compostela, SpainCellular and Molecular Cardiology Unit and Department of Cardiology, Institute of Biomedical Research of Santiago de Compostela (IDIS-SERGAS), Travesía Choupana s/n, 15706 Santiago de Compostela, SpainIt is well established that adipose tissue, apart from its energy storage function, acts as an endocrine organ that produces and secretes a number of bioactive substances, including hormones commonly known as adipokines. Obesity is a major risk factor for the development of cardiovascular diseases, mainly due to a low grade of inflammation and the excessive fat accumulation produced in this state. The adipose tissue dysfunction in obesity leads to an aberrant release of adipokines, some of them with direct cardiovascular and inflammatory regulatory functions. Inflammation is a common link between obesity and cardiovascular diseases, so this review will summarise the role of the main adipokines implicated in the regulation of the inflammatory processes occurring under the scenario of cardiovascular diseases.https://www.mdpi.com/1422-0067/21/20/7711adipokinesinflammationcardiovascular diseases |
| spellingShingle | Sandra Feijóo-Bandín Alana Aragón-Herrera Sandra Moraña-Fernández Laura Anido-Varela Estefanía Tarazón Esther Roselló-Lletí Manuel Portolés Isabel Moscoso Oreste Gualillo José Ramón González-Juanatey Francisca Lago Adipokines and Inflammation: Focus on Cardiovascular Diseases International Journal of Molecular Sciences adipokines inflammation cardiovascular diseases |
| title | Adipokines and Inflammation: Focus on Cardiovascular Diseases |
| title_full | Adipokines and Inflammation: Focus on Cardiovascular Diseases |
| title_fullStr | Adipokines and Inflammation: Focus on Cardiovascular Diseases |
| title_full_unstemmed | Adipokines and Inflammation: Focus on Cardiovascular Diseases |
| title_short | Adipokines and Inflammation: Focus on Cardiovascular Diseases |
| title_sort | adipokines and inflammation focus on cardiovascular diseases |
| topic | adipokines inflammation cardiovascular diseases |
| url | https://www.mdpi.com/1422-0067/21/20/7711 |
| work_keys_str_mv | AT sandrafeijoobandin adipokinesandinflammationfocusoncardiovasculardiseases AT alanaaragonherrera adipokinesandinflammationfocusoncardiovasculardiseases AT sandramoranafernandez adipokinesandinflammationfocusoncardiovasculardiseases AT lauraanidovarela adipokinesandinflammationfocusoncardiovasculardiseases AT estefaniatarazon adipokinesandinflammationfocusoncardiovasculardiseases AT estherrosellolleti adipokinesandinflammationfocusoncardiovasculardiseases AT manuelportoles adipokinesandinflammationfocusoncardiovasculardiseases AT isabelmoscoso adipokinesandinflammationfocusoncardiovasculardiseases AT orestegualillo adipokinesandinflammationfocusoncardiovasculardiseases AT joseramongonzalezjuanatey adipokinesandinflammationfocusoncardiovasculardiseases AT franciscalago adipokinesandinflammationfocusoncardiovasculardiseases |