Nanoparticles reduce monocytes within the lungs to improve outcomes after influenza virus infection in aged mice

Nanoparticles reduce monocytes within the lungs to improve outcomes after influenza virus infection in aged mice

Older people exhibit dysregulated innate immunity to respiratory viral infections, including influenza and SARS-CoV-2, and show an increase in morbidity and mortality. Nanoparticles are a potential practical therapeutic that could reduce exaggerated innate immune responses within the lungs during vi...

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Bibliographic Details
Main Authors: William J. Kelley, Kathleen M. Wragg, Judy Chen, Tushar Murthy, Qichen Xu, Michael T. Boyne, Joseph R. Podojil, Adam Elhofy, Daniel R. Goldstein
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-08-01
Series:JCI Insight
Subjects:
Aging
Infectious disease
Online Access:https://doi.org/10.1172/jci.insight.156320

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