Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease
Cardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may ha...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-06-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fphys.2018.00763/full |
| _version_ | 1819110381474283520 |
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| author | Dawn M. Fernandez Jose C. Clemente Jose C. Clemente Chiara Giannarelli Chiara Giannarelli Chiara Giannarelli |
| author_facet | Dawn M. Fernandez Jose C. Clemente Jose C. Clemente Chiara Giannarelli Chiara Giannarelli Chiara Giannarelli |
| author_sort | Dawn M. Fernandez |
| collection | DOAJ |
| description | Cardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may have a more important role in cardiovascular health than previously expected. This review overviews the contribution of PA to cardiovascular health, the inflammatory role of atherosclerosis, and the emerging evidence of the microbiome as a regulator of inflammation. |
| first_indexed | 2024-12-22T03:40:49Z |
| format | Article |
| id | doaj.art-4576d4188abe4cf9964dace981880ac0 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-22T03:40:49Z |
| publishDate | 2018-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-4576d4188abe4cf9964dace981880ac02022-12-21T18:40:16ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2018-06-01910.3389/fphys.2018.00763377455Physical Activity, Immune System, and the Microbiome in Cardiovascular DiseaseDawn M. Fernandez0Jose C. Clemente1Jose C. Clemente2Chiara Giannarelli3Chiara Giannarelli4Chiara Giannarelli5Department of Medicine, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesDepartment of Medicine, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesCardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may have a more important role in cardiovascular health than previously expected. This review overviews the contribution of PA to cardiovascular health, the inflammatory role of atherosclerosis, and the emerging evidence of the microbiome as a regulator of inflammation.https://www.frontiersin.org/article/10.3389/fphys.2018.00763/fullatherosclerosisinflammationmicrobiomecardiovascular diseasephysical activity |
| spellingShingle | Dawn M. Fernandez Jose C. Clemente Jose C. Clemente Chiara Giannarelli Chiara Giannarelli Chiara Giannarelli Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease Frontiers in Physiology atherosclerosis inflammation microbiome cardiovascular disease physical activity |
| title | Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease |
| title_full | Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease |
| title_fullStr | Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease |
| title_full_unstemmed | Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease |
| title_short | Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease |
| title_sort | physical activity immune system and the microbiome in cardiovascular disease |
| topic | atherosclerosis inflammation microbiome cardiovascular disease physical activity |
| url | https://www.frontiersin.org/article/10.3389/fphys.2018.00763/full |
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