Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19

Animal-derived venoms are complex mixtures of toxins triggering important biological effects during envenomings. Although venom-derived toxins are known for their potential of causing harm to victims, toxins can also act as pharmacological agents. During the COVID-19 pandemic, there was observed an...

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Main Authors: Isadora Oliveira, Isabela Ferreira, Beatriz Jacob, Kiara Cardenas, Felipe Cerni, Djane Baia-da-Silva, Eliane Arantes, Wuelton Monteiro, Manuela Pucca
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/15/2/159
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author Isadora Oliveira
Isabela Ferreira
Beatriz Jacob
Kiara Cardenas
Felipe Cerni
Djane Baia-da-Silva
Eliane Arantes
Wuelton Monteiro
Manuela Pucca
author_facet Isadora Oliveira
Isabela Ferreira
Beatriz Jacob
Kiara Cardenas
Felipe Cerni
Djane Baia-da-Silva
Eliane Arantes
Wuelton Monteiro
Manuela Pucca
author_sort Isadora Oliveira
collection DOAJ
description Animal-derived venoms are complex mixtures of toxins triggering important biological effects during envenomings. Although venom-derived toxins are known for their potential of causing harm to victims, toxins can also act as pharmacological agents. During the COVID-19 pandemic, there was observed an increase in in-depth studies on antiviral agents, and since, to date, there has been no completely effective drug against the global disease. This review explores the crosstalk of animal toxins and COVID-19, aiming to map potential therapeutic agents derived from venoms (e.g., bees, snakes, scorpions, etc.) targeting COVID-19.
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spelling doaj.art-45798a416ce64d8ca2a2486c6bcaf12c2023-11-16T23:39:21ZengMDPI AGToxins2072-66512023-02-0115215910.3390/toxins15020159Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19Isadora Oliveira0Isabela Ferreira1Beatriz Jacob2Kiara Cardenas3Felipe Cerni4Djane Baia-da-Silva5Eliane Arantes6Wuelton Monteiro7Manuela Pucca8Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, BrazilDepartment of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, BrazilDepartment of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, BrazilMedical School, Federal University of Roraima, Boa Vista 69310-000, RR, BrazilHealth Sciences Postgraduate Program, Federal University of Roraima, Boa Vista 69310-000, RR, BrazilInstitute of Clinical Research Carlos Borborema, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69850-000, AM, BrazilDepartment of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, BrazilInstitute of Clinical Research Carlos Borborema, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69850-000, AM, BrazilMedical School, Federal University of Roraima, Boa Vista 69310-000, RR, BrazilAnimal-derived venoms are complex mixtures of toxins triggering important biological effects during envenomings. Although venom-derived toxins are known for their potential of causing harm to victims, toxins can also act as pharmacological agents. During the COVID-19 pandemic, there was observed an increase in in-depth studies on antiviral agents, and since, to date, there has been no completely effective drug against the global disease. This review explores the crosstalk of animal toxins and COVID-19, aiming to map potential therapeutic agents derived from venoms (e.g., bees, snakes, scorpions, etc.) targeting COVID-19.https://www.mdpi.com/2072-6651/15/2/159SARS-CoV2COVID-19coronavirusanimal toxinsvenoms
spellingShingle Isadora Oliveira
Isabela Ferreira
Beatriz Jacob
Kiara Cardenas
Felipe Cerni
Djane Baia-da-Silva
Eliane Arantes
Wuelton Monteiro
Manuela Pucca
Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19
Toxins
SARS-CoV2
COVID-19
coronavirus
animal toxins
venoms
title Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19
title_full Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19
title_fullStr Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19
title_full_unstemmed Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19
title_short Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19
title_sort harnessing the power of venomous animal derived toxins against covid 19
topic SARS-CoV2
COVID-19
coronavirus
animal toxins
venoms
url https://www.mdpi.com/2072-6651/15/2/159
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