Adenoviral vectors stimulate glucagon transcription in human mesenchymal stem cells expressing pancreatic transcription factors.

Adenoviral vectors stimulate glucagon transcription in human mesenchymal stem cells expressing pancreatic transcription factors.

Viral gene carriers are being widely used as gene transfer systems in (trans)differentiation and reprogramming strategies. Forced expression of key regulators of pancreatic differentiation in stem cells, liver cells, pancreatic duct cells, or cells from the exocrine pancreas, can lead to the initiat...

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Bibliographic Details
Main Authors: Arnaud Zaldumbide, Françoise Carlotti, Manuel A Gonçalves, Shoshan Knaän-Shanzer, Steve J Cramer, Bart O Roep, Emmanuel J H J Wiertz, Rob C Hoeben
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23110179/?tool=EBI

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