BmK AEP, an Anti-Epileptic Peptide Distinctly Affects the Gating of Brain Subtypes of Voltage-Gated Sodium Channels

BmK AEP, an Anti-Epileptic Peptide Distinctly Affects the Gating of Brain Subtypes of Voltage-Gated Sodium Channels

BmK AEP, a scorpion peptide purified form the venom of <i>Buthus martensii</i> Karsch, has been reported to display anti-epileptic activity. Voltage-gated sodium channels (VGSCs) are responsible for the rising phase of action potentials (APs) in neurons and, therefore, controlling neuron...

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Bibliographic Details
Main Authors: Fan Zhang, Ying Wu, Xiaohan Zou, Qinglian Tang, Fang Zhao, Zhengyu Cao
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
BmK AEP
anti-epilepsy
action potentials
voltage-gated sodium channels
Online Access:https://www.mdpi.com/1422-0067/20/3/729

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