Baicalin acts as an adjuvant to potentiate the activity of azithromycin against Staphylococcus saprophyticus biofilm: an in vitro, in vivo, and molecular study

Baicalin acts as an adjuvant to potentiate the activity of azithromycin against Staphylococcus saprophyticus biofilm: an in vitro, in vivo, and molecular study

Abstract Staphylococcus saprophyticus is frequently involved in various difficult-to-treat infections due to the formation of biofilms. To identify useful antibiofilm strategies, this study explored the efficacy and mechanism of baicalin in enhancing the ability of azithromycin against multidrug-res...

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Bibliographic Details
Main Authors: Jinli Wang, Siya Li, Jinwu Meng, Jinyue Zhu, Tianxin Qiu, Wenjia Wang, Jinxue Ding, Zhenguang Liu, Kun Li, Mujahid lqbal, Deyun Wang, Yi Wu, Jiaguo Liu
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Veterinary Research
Subjects:
S. saprophyticus
baicalin
azithromycin
biofilm
WalK/R system
Online Access:https://doi.org/10.1186/s13567-022-01088-z

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